Department of Urology, Boston Medical Center, Boston, MA.
Department of Urology, Boston Medical Center, Boston, MA.
Urology. 2020 Jul;141:125-129. doi: 10.1016/j.urology.2020.04.054. Epub 2020 Apr 22.
To compare the accuracy of prostate sizing between pelvic abdominal (PUS) and transrectal (TRUS) ultrasound in a large, diverse cohort of men at our institution. Prostate volume plays a vital role in all types of prostate disease. American Urological Association guidelines (2018) for surgical management of benign prostatic hyperplasia now include consideration of prostate volume measurement prior to surgical intervention. Ultrasound is a quick and radiation-free imaging modality.
We performed a single-center, retrospective study of 299 patients with prostate sizing between January 1, 2012 and August 31, 2017. Prostate volume was derived from ellipsoid volume calculation using dimensions measured on ultrasound. PUS and TRUS were compared by calculating the Pearson correlation coefficient and intraclass correlation coefficient, and agreement between modalities assessed using the Bland Altman analysis. This analysis was done for the whole sample population as well as for specific groupings according to body mass index, prostate size, and time between exams.
A total of 236 patients had PUS followed by TRUS and met study inclusion criteria. Median age was 63, median prostate specific antigen value prior to PUS was 7.6 ng/mL, and only 20% were white. Mean volume differences between the two modalities for the data (vol - vol) were (-0.3 ± 1.1) cm. Bland-Altman analysis showed agreement between PUS and TRUS only for prostates ≤ 30 cm.
For prostates less than 30 cc, we found that PUS is interchangeable with TRUS in estimating prostate volume. However, for larger prostates where size may alter surgical management, we would recommend TRUS or cross-sectional imaging.
比较我院大型、多样化男性群体中经腹盆腔超声(PUS)和经直肠超声(TRUS)前列腺测量的准确性。前列腺体积在所有类型的前列腺疾病中都起着至关重要的作用。美国泌尿外科学会(AUA)2018 年关于良性前列腺增生手术治疗的指南现在包括在手术干预前考虑前列腺体积测量。超声是一种快速、无辐射的成像方式。
我们对 2012 年 1 月 1 日至 2017 年 8 月 31 日期间进行前列腺测量的 299 例患者进行了单中心回顾性研究。前列腺体积通过在超声测量的尺寸上使用椭圆体积计算公式得出。通过计算 Pearson 相关系数和组内相关系数比较 PUS 和 TRUS,通过 Bland-Altman 分析评估两种方式之间的一致性。对全样本人群以及根据体重指数、前列腺大小和检查时间进行特定分组进行了此分析。
共有 236 例患者行 PUS 后行 TRUS,符合研究纳入标准。中位年龄为 63 岁,PUS 前中位前列腺特异性抗原值为 7.6ng/ml,只有 20%为白人。两种方式的平均体积差异(vol-vol)为(-0.3±1.1)cm。Bland-Altman 分析显示,仅当前列腺体积≤30cm 时,PUS 与 TRUS 之间存在一致性。
对于小于 30cc 的前列腺,我们发现 PUS 可与 TRUS 互换用于估计前列腺体积。然而,对于体积可能改变手术管理的较大前列腺,我们建议使用 TRUS 或横断面成像。