墨西哥粘质沙雷氏菌耐药性监测
Surveillance of antimicrobial resistance in Serratia marcescens in Mexico.
作者信息
González Gloria M, de J Treviño-Rangel Rogelio, Campos Christian L, Villanueva-Lozano Hiram, Bonifaz Alexandro, Franco-Cendejas Rafael, López-Jácome Luis E, Bobadilla Del Valle Miriam, Llaca-Díaz Jorge M, Ayala-Gaytán Juan J, Castañón-Olivares Laura R, Tinoco Juan C, Andrade Angel
机构信息
Departamento de Microbiología, Facultad de Medicina y Hospital Universitario "Dr José Eleuterio González", Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.
Servicio de Dermatología y Departamento de Micología, Hospital General de México "Dr. Eduardo Liceaga", Mexico City, Mexico.
出版信息
New Microbiol. 2020 Jan;43(1):34-37. Epub 2019 Dec 13.
Antimicrobial resistance is a global public health threat. Therefore, surveillance studies are important tools to help direct antimicrobial use. The aim of this study was to investigate antimicrobial resistance in Serratia marcescens isolates collected in 2016-2017 at eight medical centers from two regions of Mexico. Selected S. marcescens isolates were further tested by polymerase chain reaction to detect the presence of genes encoding the β-lactamases, SHV, TEM or CTX. Antimicrobial resistance continues to be high in Mexico, particularly to ciprofloxacin and aminoglycosides. Also, a widespread prevalence of blaTEM was detected in S. marcescens isolates.
抗菌药物耐药性是全球公共卫生威胁。因此，监测研究是有助于指导抗菌药物使用的重要工具。本研究的目的是调查2016 - 2017年在墨西哥两个地区的八个医疗中心收集的粘质沙雷氏菌分离株中的抗菌药物耐药性。对选定的粘质沙雷氏菌分离株进一步进行聚合酶链反应检测，以检测编码β-内酰胺酶、SHV、TEM或CTX的基因的存在。墨西哥的抗菌药物耐药性仍然很高，尤其是对环丙沙星和氨基糖苷类药物。此外，在粘质沙雷氏菌分离株中检测到blaTEM的广泛流行。
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