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肝-肺联合移植的麻醉。

Anesthesia for combined liver-thoracic transplantation.

机构信息

Department of Anesthesiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

Department of Surgery, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

出版信息

Best Pract Res Clin Anaesthesiol. 2020 Mar;34(1):101-108. doi: 10.1016/j.bpa.2020.01.001. Epub 2020 Jan 25.

DOI:10.1016/j.bpa.2020.01.001
PMID:32334780
Abstract

The combined transplantation of a thoracic organ and the liver is performed in patients with dual-organ failure in whom survival is not expected with single-organ transplantation alone. Although uncommonly performed, the number of combined liver-lung and liver-heart transplants is increasing. Anesthetic management of this complex procedure is challenging. Major blood loss, prolonged operation time, difficult weaning of cardiopulmonary bypass and coagulation disturbances are common. Despite the complexity of surgery, the outcome is comparable to single-organ transplant.

摘要

在单一器官移植不能预期存活的双器官衰竭患者中,会进行胸部器官和肝脏的联合移植。虽然联合肝肺和心肝移植并不常见,但数量在不断增加。这种复杂手术的麻醉管理极具挑战性。大量失血、手术时间延长、心肺转流脱机困难和凝血功能紊乱较为常见。尽管手术复杂,但结果与单一器官移植相当。

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