Malalties Infeccioses i Resposta Inflamatòria Sistèmica en Pediatria, Unitat d´Infeccions, Servei de Pediatria, Institut de Recerca Pediàtrica Hospital Sant Joan de Déu, Barcelona, Spain.
Pediatric Infectious Diseases Unit, Gregorio Marañón Hospital, Madrid, Spain.
J Pediatr. 2020 Aug;223:212-215.e1. doi: 10.1016/j.jpeds.2020.02.025. Epub 2020 Apr 22.
In 2016, a new interferon-gamma release assay, QuantiFERON-TB Gold Plus, was introduced. We conducted a cross-sectional multicenter study, involving 158 children and adolescents with tuberculosis disease. The overall sensitivity of the assay was 82.9% (IQR 77.0%-88.8%), indicating that in children this test does not have higher sensitivity than previous generation interferon-gamma release assays.
2016 年，引入了一种新的干扰素-γ释放检测方法，即 QuantiFERON-TB Gold Plus。我们进行了一项横断面多中心研究，涉及 158 例结核病患儿和青少年。该检测方法的总体灵敏度为 82.9%（IQR 77.0%-88.8%），表明在儿童中，该检测方法的灵敏度并不高于前一代干扰素-γ释放检测方法。
