新一代 QuantiFERON-TB Gold plus 与之前的测试版本 QuantiFERON-TB Gold IT 直接比较，具有同等的敏感性。
Equal sensitivity of the new generation QuantiFERON-TB Gold plus in direct comparison with the previous test version QuantiFERON-TB Gold IT.
机构信息
Synlab MVZ Gauting, Zweigniederlassung der synlab MVZ Augsburg GmbH, Gauting, Germany; IML red GmbH, Institute of Microbiology and Laboratory Medicine, WHO Supranational Reference Laboratory of Tuberculosis, Gauting, Germany.
Asklepios Fachkliniken München Gauting, Infectious Disease Department, Gauting, Germany.
出版信息
Clin Microbiol Infect. 2016 Aug;22(8):701-3. doi: 10.1016/j.cmi.2016.05.006. Epub 2016 May 13.
QuantiFERON-TB Gold IT analyses interferon-γ release from CD4(+) T cells after stimulation with specific tuberculosis (TB) antigens. Its sensitivity is approximately 80% for active TB. A new test generation (QFTGplus) also analyses the response of CD8(+) T cells. We investigated both test generations in a direct head-to-head comparison in a German pulmonary hospital. Sensitivity rates for active TB were identical, no matter whether diagnosis was bacteriologically confirmed or not.
QuantiFERON-TB Gold IT 通过分析 CD4(+) T 细胞在受到特定结核分枝杆菌（TB）抗原刺激后的干扰素-γ释放来进行检测。其对活动性结核病的灵敏度约为 80%。新一代的检测方法（QFTGplus）还可以分析 CD8(+) T 细胞的反应。我们在德国一家肺病医院进行了直接的头对头比较，研究了这两种检测方法。无论诊断是否经过细菌学确认，对于活动性结核病，两种检测方法的灵敏度率都相同。
Zotero 插件