Rijzewijk J J, Boezeman J B, Bauer F W
Department of Dermatology, University of Nijmegen, The Netherlands.
Cell Tissue Kinet. 1988 Jul;21(4):227-9. doi: 10.1111/j.1365-2184.1988.tb00782.x.
A recent investigation of the hyperproliferative activity of human epidermis following sellotape stripping showed a wave of cell divisions with a maximal percentage of cells in mid-S phase at about 39 h after stripping. Here we present a study over the period of 52-76 h following stripping, showing a second wave of cell divisions with a maximal percentage of cells in mid-S at about 63 h. This indicates an average cell cycle time of about 23 h. Human epidermis after tape-stripping provides us with a useful model of synchronized growth, allowing us to study drug influences on cell kinetics accurately.
最近一项关于透明胶带剥离后人表皮增殖活性的研究表明，剥离后约39小时出现一波细胞分裂，处于S期中期的细胞百分比最高。在此，我们展示了一项在剥离后52 - 76小时期间的研究，结果显示在约63小时出现第二波细胞分裂，处于S期中期的细胞百分比最高。这表明平均细胞周期时间约为23小时。胶带剥离后的人表皮为我们提供了一个同步生长的有用模型，使我们能够准确研究药物对细胞动力学的影响。
