危重症儿童的抗病毒药物
Antiviral agents in the critically ill child.
作者信息
Munoz Flor M
机构信息
Departments of Microbiology and Immunology, and Pediatrics, Baylor College of Medicine, Houston, TX.
出版信息
Semin Pediatr Infect Dis. 2000 Jan;11(1):35-42. doi: 10.1053/spid.0110035. Epub 2005 Nov 2.
Abstract
The treatment for most viral infections in children primarily is supportive. Severe viral illnesses and significant secondary complications that require treatment in the intensive care unit may occur in immunocompromised patients and also in infants and children who were previously healthy. Antiviral agents with specific activity against certain respiratory viruses, herpesviruses, and enteric viruses are available. New drugs are under development, and their use in pediatric patients is a subject of active research. The clinician's knowledge of the mechanisms of action, spectrum of activity, and side effects of these drugs is an important tool for their judicious use in the treatment of the critically ill child. .
摘要
儿童大多数病毒感染的治疗主要是支持性的。免疫功能低下的患者以及先前健康的婴幼儿可能会出现需要在重症监护病房治疗的严重病毒性疾病和严重的继发性并发症。有针对某些呼吸道病毒、疱疹病毒和肠道病毒具有特定活性的抗病毒药物。新药正在研发中，其在儿科患者中的应用是一个积极研究的课题。临床医生对这些药物的作用机制、活性谱和副作用的了解是明智地用于治疗重症儿童的重要工具。
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