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一项针对学龄儿童内化症状的跨诊断指示性预防的12个月随访:EMOTION研究结果

A 12-month follow-up of a transdiagnostic indicated prevention of internalizing symptoms in school-aged children: the results from the EMOTION study.

作者信息

Loevaas M E S, Lydersen S, Sund A M, Neumer S-P, Martinsen K D, Holen S, Patras J, Adolfsen F, Rasmussen L-M P, Reinfjell T

机构信息

1Department of Psychology, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.

2Department of Child and Adolescent Psychiatry, St. Olavs University Hospital, Trondheim, Norway.

出版信息

Child Adolesc Psychiatry Ment Health. 2020 Apr 22;14:15. doi: 10.1186/s13034-020-00322-w. eCollection 2020.

Abstract

BACKGROUND

Anxious and depressive symptoms in youth are highly prevalent, are often comorbid and have a high rate of relapse. Preventive interventions are promising, but follow-up results are lacking. The transdiagnostic EMOTION program is an indicated preventive cognitive behavioral therapy (CBT) intervention targeting children aged 8-12 years.

METHODS

The present study investigates the 12 months follow-up effects of the EMOTION intervention in a cluster randomized controlled trial (RCT) with 795 children that included both child self-reports and parental reports.

RESULTS

Mixed model analyses showed a larger decrease of symptoms in the intervention group than in the control group for child self-reported anxious symptoms (The Multidimensional Anxiety Scale for Children (MASC) difference 4.56, CI 1.83 to 7.29, = .001). Parental reports for both anxious (MASC difference 2.50, CI .26 to 4.74, = .029) and depressive (The Mood and Feelings Questionnaire-short form (SMFQ) difference 1.55, CI .83 to 2.26, ≤ .001) symptoms in children also showed a reduction. No statistically significant difference was found for child self-reported depressive symptoms (SMFQ difference .69, CI - .22 to 1.60, = .139).

CONCLUSION

The transdiagnostic EMOTION program has shown the potential for long-term reductions in symptoms of both anxiety and depression in school-aged children. However, results regarding depressive symptoms must be considered preliminary as only parental report indicated effect. The regional ethics committee (REC) of Norway approved the study. Registration number: 2013/1909; Project title: Coping Kids: a randomized controlled study of a new indicated preventive intervention for children with symptoms of anxiety and depression. ClinicalTrials.gov Identifier; NCT02340637.

摘要

背景

青少年的焦虑和抑郁症状非常普遍,常常合并出现,且复发率很高。预防性干预措施前景广阔,但缺乏后续跟踪结果。跨诊断情绪项目是一项针对8至12岁儿童的指定预防性认知行为疗法(CBT)干预措施。

方法

本研究在一项包含795名儿童的整群随机对照试验(RCT)中调查了情绪干预措施的12个月后续效果,该试验包括儿童自我报告和家长报告。

结果

混合模型分析显示,干预组儿童自我报告的焦虑症状(儿童多维焦虑量表(MASC)差异为4.56,置信区间为1.83至7.29,P = 0.001)的症状减轻幅度大于对照组。家长报告的儿童焦虑(MASC差异为2.50,置信区间为0.26至4.74,P = 0.029)和抑郁(情绪与感受问卷简版(SMFQ)差异为1.55,置信区间为0.83至2.26,P≤0.001)症状也有所减轻。儿童自我报告的抑郁症状(SMFQ差异为0.69,置信区间为 -0.22至1.60,P = 0.139)未发现统计学上的显著差异。

结论

跨诊断情绪项目已显示出在学龄儿童中长期减轻焦虑和抑郁症状的潜力。然而,关于抑郁症状的结果仅基于家长报告显示有效果,因此必须视为初步结果。挪威地区伦理委员会(REC)批准了该研究。注册号:2013/1909;项目标题:应对儿童:一项针对有焦虑和抑郁症状儿童的新型指定预防性干预措施的随机对照研究。ClinicalTrials.gov标识符:NCT02340637。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b666/7178617/6913b8e84362/13034_2020_322_Fig1_HTML.jpg

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