Padmanaban Varun, Hussein Rezhan, Rizk Elias
Neurological Surgery, Penn State Milton S. Hershey Medical Center, Hershey, USA.
Medicine/Infectious Disease, Penn State Milton S. Hershey Medical Center, Hershey, USA.
Cureus. 2020 Mar 24;12(3):e7398. doi: 10.7759/cureus.7398.
Central nervous system infections with nontuberculous mycobacteria (NTM) are rare but have been increasing in frequency. A small fraction of these infections are related to surgical hardware, with approximately 20 cases reported. Patients typically present with an indolent course but can rapidly deteriorate. We report two novel cases of NTM infection in ventriculoperitoneal shunts, and review the literature on treatment options, challenges and outcomes in these patients. Clinicians should consider NTM when dealing with unusual hardware infections as it is an emerging infectious disease with high potential for morbidity and mortality.
非结核分枝杆菌（NTM）引起的中枢神经系统感染较为罕见，但发病率一直在上升。这些感染中有一小部分与外科植入物有关，已报告的病例约有20例。患者通常病程进展缓慢，但也可能迅速恶化。我们报告了两例脑室腹腔分流术中NTM感染的新病例，并回顾了关于这些患者治疗选择、挑战及预后的文献。临床医生在处理不寻常的植入物感染时应考虑NTM，因为它是一种新兴的传染病，具有较高的发病和死亡风险。
