囊性纤维化中的非结核分枝杆菌感染。
Nontuberculous mycobacterial infections in cystic fibrosis.
机构信息
Department of Pediatrics, Children's Hospital Colorado, University of Colorado Denver School of Medicine, 13123 East 16th Avenue, B-395, Aurora, CO 80045, USA.
Department of Medicine, National Jewish Health, University of Colorado Denver, 1400 Jackson Street, Denver, CO 80206, USA.
出版信息
Clin Chest Med. 2015 Mar;36(1):101-15. doi: 10.1016/j.ccm.2014.11.003.
Nontuberculous mycobacteria (NTM) are important emerging cystic fibrosis (CF) pathogens. Factors including the steady aging of the CF population, the apparent increase of NTM in the environment, and the potential for patient-to-patient transmission, may contribute to increased acquisition. Diagnosis of NTM disease is challenging due to disease overlap; thus, comprehensive care of the CF patient must be optimized to assess the clinical impact of the NTM (indolent versus active), and to improve response to treatment. The development of a CF-specific approach to the diagnosis and treatment of NTM infection is a research priority for the CF community.
非结核分枝杆菌（NTM）是重要的新兴囊性纤维化（CF）病原体。包括 CF 人群的稳步老龄化、环境中 NTM 的明显增加以及患者之间传播的可能性在内的多种因素，可能导致 NTM 的感染率增加。由于疾病存在重叠，因此 NTM 疾病的诊断具有挑战性；因此，必须优化 CF 患者的综合护理，以评估 NTM 的临床影响（惰性与活跃），并提高治疗反应。为 CF 患者制定针对 NTM 感染的诊断和治疗的特定方法，是 CF 社区的一项研究重点。
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