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本文引用的文献

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Miliary metastases are associated with epidermal growth factor receptor mutations in non-small cell lung cancer: a population-based study.粟粒性转移与非小细胞肺癌中的表皮生长因子受体突变相关：一项基于人群的研究。
Acta Oncol. 2017 Sep;56(9):1175-1180. doi: 10.1080/0284186X.2017.1328128. Epub 2017 May 19.
2
EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure.欧洲肝脏研究学会急性（暴发性）肝衰竭管理临床实践指南。
J Hepatol. 2017 May;66(5):1047-1081. doi: 10.1016/j.jhep.2016.12.003.
3
Malignant infiltration of the liver presenting as acute liver failure.表现为急性肝衰竭的肝脏恶性浸润。
Clin Gastroenterol Hepatol. 2015 May;13(5):1025-8. doi: 10.1016/j.cgh.2014.09.040. Epub 2014 Sep 30.
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Miliary hepatic metastases from neuroendocrine carcinoma.神经内分泌癌的粟粒性肝转移
Dig Surg. 2008;25(5):330. doi: 10.1159/000158907. Epub 2008 Oct 1.
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Inactivation of the E-cadherin-mediated cell adhesion system in human cancers.人类癌症中E-钙黏蛋白介导的细胞黏附系统的失活
Am J Pathol. 1998 Aug;153(2):333-9. doi: 10.1016/S0002-9440(10)65575-7.
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Acute liver failure secondary to hepatic infiltration: a single centre experience of 18 cases.继发于肝脏浸润的急性肝衰竭：单中心18例经验
Gut. 1998 Apr;42(4):576-80. doi: 10.1136/gut.42.4.576.
7
Disappearing intrahepatic bile ducts: the syndromes and their mechanisms.肝内胆管消失综合征：综合征及其机制
Semin Liver Dis. 1993 Aug;13(3):261-75. doi: 10.1055/s-2007-1007354.
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Fulminant hepatic failure: an unusual presentation of metastatic liver disease.暴发性肝衰竭：转移性肝病的一种罕见表现。
Gastroenterology. 1981 Apr;80(4):820-5.
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Massive blastic infiltration of the liver: a cause of fulminant hepatic failure.
Hepatology. 1983 May-Jun;3(3):428-32. doi: 10.1002/hep.1840030324.
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Hepatic involvement in Hodgkin's disease. Clues to histologic diagnosis.
Cancer. 1989 Nov 15;64(10):2121-6. doi: 10.1002/1097-0142(19891115)64:10<2121::aid-cncr2820641025>3.0.co;2-l.

粟粒性肝转移导致的急性肝衰竭

Acute Liver Failure due to Miliary Liver Metastasis.

作者信息

Lavender Charles A, Stout Jessica, Chung Hui-Yong, Johnson Michael, Thandassery Ragesh B

机构信息

Division of Gastroenterology, Department of Medicine, Central Arkansas Veterans Health Care System, Little Rock, AR.

Diagnostic and Therapeutic Imaging Services, Central Arkansas Veterans Health Care System, Little Rock, AR.

出版信息

ACG Case Rep J. 2020 Mar 16;7(3):e00294. doi: 10.14309/crj.0000000000000294. eCollection 2020 Mar.

DOI:10.14309/crj.0000000000000294
PMID:32337299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7162133/
Abstract

Acute liver failure (ALF) is a medical emergency with high mortality. Accurate etiological diagnosis, intensive liver support, and liver transplantation are critical for the management of these patients. Malignant infiltration of the liver uncommonly results in ALF. Diffuse infiltration can be missed by imaging, particularly in early stages, and biopsy is often required to clinch the diagnosis. We report a case of ALF due to diffuse liver metastasis.

摘要

急性肝衰竭（ALF）是一种死亡率很高的内科急症。准确的病因诊断、强化肝脏支持和肝移植对于这些患者的治疗至关重要。肝脏的恶性浸润很少导致ALF。影像学检查可能会漏诊弥漫性浸润，尤其是在早期阶段，通常需要活检来确诊。我们报告一例因肝脏弥漫性转移导致急性肝衰竭的病例。