Boggero Ian A, Rojas Ramirez Marcia V, King Christopher D
Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Department of Oral Health Science, College of Dentistry, University of Kentucky, Lexington, Kentucky.
Pain Med. 2020 Sep 1;21(9):1961-1970. doi: 10.1093/pm/pnaa092.
Mental, emotional, physical, and general fatigue, as well as vigor, have each been associated with pain interference-defined as pain-related disruption of social, recreational, and work-related activities-in patients with chronic orofacial pain (COFP). The objectives of the current study were to compare levels of these fatigue subtypes across younger, middle-aged, and older patients with COFP and test the associations between fatigue subtypes and pain interference in these age groups.
A cross-sectional cohort design was used.
Participants self-reported fatigue subtypes (Multidimensional Fatigue Symptom Inventory-Short Form), pain interference (West Haven-Yale Multidimensional Pain Inventory), pain intensity (visual analog scale), pain duration (months), depression (Symptom Checklist 90-Revised), and sleep quality (Pittsburgh Sleep Quality Index) at their initial appointment at a tertiary orofacial pain clinic.
Sixty younger (age 18-39), 134 middle-aged (age 40-59), and 51 older (age 60-79) COFP patients provided data for the study.
Analysis of variance was used to compare levels of fatigue subtypes between the age groups. Regression with dummy-coding was used to test if the relationship between fatigue subtypes and pain interference varied by age.
Older COFP patients reported less general fatigue and more vigor than younger or middle-aged adults. Fatigue subtypes were each associated with greater pain interference, but associations became nonsignificant after controlling for depression, sleep, and pain intensity/duration. Age group-by-fatigue subtype interactions were not observed.
Managing fatigue may be important to reduce pain interference in COFP populations and may be accomplished in part by improving depression and sleep.
在慢性口面部疼痛（COFP）患者中，精神、情绪、身体和总体疲劳以及活力均与疼痛干扰相关，疼痛干扰被定义为与疼痛相关的社会、娱乐和工作相关活动的中断。本研究的目的是比较年轻、中年和老年COFP患者这些疲劳亚型的水平，并测试这些年龄组中疲劳亚型与疼痛干扰之间的关联。
采用横断面队列设计。
参与者在三级口面部疼痛诊所首次就诊时自我报告疲劳亚型（多维疲劳症状量表简表）、疼痛干扰（西黑文-耶鲁多维疼痛量表）、疼痛强度（视觉模拟量表）、疼痛持续时间（月）、抑郁（症状自评量表90修订版）和睡眠质量（匹兹堡睡眠质量指数）。
60名年轻（18-39岁）、134名中年（40-59岁）和51名老年（60-79岁）COFP患者为该研究提供了数据。
采用方差分析比较各年龄组之间的疲劳亚型水平。使用虚拟编码回归来测试疲劳亚型与疼痛干扰之间的关系是否因年龄而异。
老年COFP患者报告的总体疲劳比年轻或中年成年人少，活力更多。每种疲劳亚型都与更大的疼痛干扰相关，但在控制了抑郁、睡眠和疼痛强度/持续时间后，这种关联变得不显著。未观察到年龄组与疲劳亚型之间的相互作用。
管理疲劳对于减少COFP人群的疼痛干扰可能很重要，并且可以部分通过改善抑郁和睡眠来实现。
