Mele G, Loizzi P, Greco P, Gargano G, Varcaccio Garofalo G, Belsanti A
II Obstetric and Gynecology Clinic, University of Bari, Italy.
Clin Exp Obstet Gynecol. 1988;15(4):154-6.
Three different regimens of antibiotic treatment have been employed in order to evaluate their efficacy as a profilaxis for abdominal hysterectomy. Two short term administrations (Cephtriaxone and Cephamandole plus Tobramycine) and a conventional full dose treatment (Cephazoline) have been compared over a group of homogeneous patients. No significant differences, except a reduction in postoperative time spent in hospital, have been found among the groups. A reduction in urinary tract infection has also been reported with a single-dose antibiotic prophylaxis.
为评估三种不同抗生素治疗方案作为腹部子宫切除术预防性用药的疗效,我们进行了相关研究。在一组情况相似的患者中,对比了两种短期给药方案(头孢曲松、头孢孟多加妥布霉素)和一种传统全剂量治疗方案(头孢唑林)。结果发现,除了术后住院时间缩短外,各治疗组之间没有显著差异。此外,有报告称单剂量抗生素预防性用药可降低尿路感染的发生率。