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糖尿病中的血浆碱性磷酸酶同工酶

Plasma alkaline phosphatase isoenzymes in diabetes mellitus.

作者信息

Tibi L, Collier A, Patrick A W, Clarke B F, Smith A F

机构信息

University Department of Clinical Chemistry, Royal Infirmary, Edinburgh, Scotland, UK.

出版信息

Clin Chim Acta. 1988 Oct 14;177(2):147-55. doi: 10.1016/0009-8981(88)90136-2.

DOI:10.1016/0009-8981(88)90136-2
PMID:3233764
Abstract

Alkaline phosphatase (ALP) isoenzymes were measured in type 1 diabetics, type 2 diabetics and in a non-diabetic control group. Within the diabetics and the control group, intestinal ALP activity was significantly higher in BO secretors than A secretors or ABO non-secretors. There was no difference in intestinal ALP activity between type 1 and type 2 diabetics but the diabetics had a significantly higher activity of this isoenzyme than the corresponding blood group/secretor status category of the control group. Liver ALP was significantly higher in the diabetics compared with the control group. Bone ALP showed no significant difference between the diabetics and the control group.

摘要

对1型糖尿病患者、2型糖尿病患者和非糖尿病对照组进行了碱性磷酸酶(ALP)同工酶检测。在糖尿病患者组和对照组中,BO分泌型者的肠道ALP活性显著高于A分泌型者或ABO非分泌型者。1型和2型糖尿病患者的肠道ALP活性没有差异,但糖尿病患者的这种同工酶活性显著高于对照组相应血型/分泌状态类别者。与对照组相比,糖尿病患者的肝脏ALP显著更高。糖尿病患者和对照组之间的骨ALP没有显著差异。

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