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认知与社会人口学因素对癌症疼痛患者有效止痛的影响:中国一项横断面调查。

Cognition and Sociodemographic Determinants for Effective Pain Control in Patients with Cancer Pain: a Cross-sectional Survey in China.

机构信息

School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

出版信息

Curr Med Sci. 2020 Apr;40(2):249-256. doi: 10.1007/s11596-020-2167-3. Epub 2020 Apr 26.

Abstract

This cross-sectional study aimed to investigate cancer patients' cognitive level of pain control and to evaluate the patient-related factors or barriers to effective cancer pain management in China. In seven tertiary hospitals across China, 372 patients experiencing cancer pain were surveyed through a self-designed questionnaire to assess the factors associated with effective pain control. Patients' demographic data and pain control-related factors were recorded. Cluster sampling and binary logistic regression models were used to investigate the association between predictive factors and effective pain control. The survey showed that the majority of the patients were more than 45 years old (76.3%), and 64.4% had an average annual income of more than 20 000 RMB. One-third of the patients suffered from cancer pain for more than 3 months, and 75.1% received professional guidance during medication. The barriers to pain control for patients included preference to enduring pain and refusing analgesics (62.9%), negligence towards drug usage (28.5%), concerns about the addiction (48.2%) and adverse reaction (56.4%). The average annual family income, professional guidance, knowledge of pain medication, adherence to analgesics, and concerns about addiction to analgesics were significantly correlated to the effect of patients' pain control. The study presents major barriers to optimal pain control among patients with cancer in China. Our findings suggest that educational programs and medical insurance reimbursement support from the government are urgently needed to overcome the cognitive barriers toward effective pain management and to relieve the economic burden among patients with cancer pain in China.

摘要

本横断面研究旨在调查癌症患者对疼痛控制的认知水平,并评估中国癌症患者有效疼痛管理的相关患者因素或障碍。在中国的七所三级医院中,通过自行设计的问卷对 372 名经历癌痛的患者进行调查,以评估与有效疼痛控制相关的因素。记录患者的人口统计学数据和疼痛控制相关因素。采用聚类抽样和二元逻辑回归模型来研究预测因素与有效疼痛控制之间的关联。调查显示,大多数患者年龄在 45 岁以上(76.3%),64.4%的人年收入超过 20000 元人民币。三分之一的患者经历癌症疼痛超过 3 个月,75.1%的患者在用药期间接受了专业指导。患者控制疼痛的障碍包括偏爱忍受疼痛和拒绝止痛药(62.9%)、忽视药物使用(28.5%)、担心成瘾(48.2%)和不良反应(56.4%)。年家庭收入、专业指导、疼痛药物知识、对止痛药的依从性以及对止痛药成瘾的担忧与患者疼痛控制效果显著相关。本研究提出了中国癌症患者最佳疼痛控制的主要障碍。我们的研究结果表明,迫切需要开展教育项目并获得政府的医疗保险报销支持,以克服对有效疼痛管理的认知障碍,并减轻中国癌症疼痛患者的经济负担。

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