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Pathophysiology and clinical characteristics of pain in most common locations in cancer patients.癌症患者最常见部位疼痛的病理生理学和临床特征
J Physiol Pharmacol. 2016 Dec;67(6):787-799.
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Bone cancer pain: causes, consequences, and therapeutic opportunities.骨癌疼痛:病因、后果与治疗机遇。
Pain. 2013 Dec;154 Suppl 1:S54-S62. doi: 10.1016/j.pain.2013.07.044. Epub 2013 Jul 31.
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Cancer pain in Jordan: prevalence and adequacy of treatment.约旦的癌症疼痛:患病率与治疗的充分性
Int J Palliat Nurs. 2013 Mar;19(3):125-30. doi: 10.12968/ijpn.2013.19.3.125.
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Physical symptom profile for adult cancer inpatients at a Lebanese cancer unit.黎巴嫩癌症中心成年癌症住院患者的躯体症状特征。
Eur J Intern Med. 2012 Dec;23(8):e185-9. doi: 10.1016/j.ejim.2012.08.018. Epub 2012 Sep 23.
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Prevalence and management of pain by different age groups of Korean cancer patients.韩国癌症患者不同年龄组疼痛的患病率及管理情况
Am J Hosp Palliat Care. 2013 Jun;30(4):393-8. doi: 10.1177/1049909112452624. Epub 2012 Jul 9.
6
Symptom prevalence and management of cancer patients in Lebanon.黎巴嫩癌症患者的症状发生率及处理。
J Pain Symptom Manage. 2012 Sep;44(3):386-99. doi: 10.1016/j.jpainsymman.2011.10.019. Epub 2012 Jun 22.
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Patient-related barriers to cancer pain management in Jordan.约旦癌症疼痛管理中与患者相关的障碍。
J Pediatr Hematol Oncol. 2012 Mar;34 Suppl 1:S28-31. doi: 10.1097/MPH.0b013e318249ad34.
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Psychometric evaluation of the arabic brief pain inventory in a sample of Lebanese cancer patients.黎巴嫩癌症患者样本中阿拉伯文简明疼痛量表的心理计量学评估。
J Pain Symptom Manage. 2011 Jul;42(1):147-54. doi: 10.1016/j.jpainsymman.2010.09.019. Epub 2011 Mar 12.
9
Pain in cancer patients: the Greek experience.癌症患者的疼痛:希腊的经验。
Eur J Oncol Nurs. 2011 Dec;15(5):442-6. doi: 10.1016/j.ejon.2010.10.008. Epub 2010 Nov 18.
10
First evidence of oncologic neuropathic pain prevalence after screening 8615 cancer patients. Results of the On study.首次筛查 8615 例癌症患者后的肿瘤神经性疼痛患病率证据。On 研究结果。
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癌症相关疼痛:中东地区一家三级医疗中心的患病率、严重程度及管理

Cancer-Related Pain: Prevalence, Severity and Management in a Tertiary Care Center in the Middle East.

作者信息

Hamieh Nadine M, Akel Reem, Anouti Bilal, Traboulsi Cindy, Makki Iman, Hamieh Lana, Tfayli Arafat

机构信息

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Email:

出版信息

Asian Pac J Cancer Prev. 2018 Mar 27;19(3):769-775. doi: 10.22034/APJCP.2018.19.3.769.

DOI:10.22034/APJCP.2018.19.3.769
PMID:29582633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5980854/
Abstract

Background: Despite pain awareness and the development of treatment guidelines, cancer-related pain assessment and management remain suboptimal. Our objectives were to estimate the prevalence and severity of pain and its interference with daily activities, and evaluate adequacy of treatment in cancer patients in Lebanon. Methods: A total of 400 cancer patients aged 18 and above were interviewed at the American University of Beirut Medical Center surgical and medical oncology floors, outpatient clinics and chemotherapy units from March 2016-February 2017. The subjects covered were socio-demographics, clinical data, and presence of pain in the past month with use of the Brief Pain Inventory questionnaire. Descriptive statistics were conducted using t-test, chi-square and Fischer’s exact tests. Pearson’s correlation coefficients were used to examine relationships between pain severity and pain interference. Logistic regression was employed to determine risk factors for pain. Results: The majority of participants were Lebanese (76.0%), females (62.7%), married (80.2%), of Muslim faith (64.2%), of urban residence (85.8%), and with insurance plans (81.3%). Most had breast cancer (38.8%), were stage 4 (52.7%) and underwent a combination of surgery and systemic therapy (55.1%). The prevalence of pain in the past month was 29.8%. Among patients with pain, the highest proportion had moderate pain (37.8%) and around 46% received inadequate treatment. Conclusion: More awareness about cancer-related pain is needed to improve pain management and encourage referral to palliative care and pain specialists early-on in diagnosis of disease.

摘要

背景

尽管人们对疼痛有所认识,且制定了治疗指南,但癌症相关疼痛的评估和管理仍不尽人意。我们的目标是估计疼痛的患病率、严重程度及其对日常活动的干扰,并评估黎巴嫩癌症患者的治疗充分性。方法:2016年3月至2017年2月期间,在贝鲁特美国大学医学中心的外科和内科肿瘤病房、门诊诊所和化疗科室,对400名18岁及以上的癌症患者进行了访谈。涵盖的主题包括社会人口统计学、临床数据,以及使用简明疼痛问卷评估过去一个月内是否存在疼痛。使用t检验、卡方检验和费舍尔精确检验进行描述性统计。采用皮尔逊相关系数检验疼痛严重程度与疼痛干扰之间的关系。采用逻辑回归确定疼痛的危险因素。结果:大多数参与者为黎巴嫩人(76.0%)、女性(62.7%)、已婚(80.2%)、穆斯林信仰(64.2%)、城市居民(85.8%)且有保险计划(81.3%)。大多数患有乳腺癌(38.8%),处于4期(52.7%),并接受了手术和全身治疗相结合的方案(55.1%)。过去一个月内疼痛的患病率为29.8%。在疼痛患者中,比例最高的是中度疼痛(37.8%),约46%的患者接受了不充分的治疗。结论:需要提高对癌症相关疼痛的认识,以改善疼痛管理,并鼓励在疾病诊断早期就转诊至姑息治疗和疼痛专科医生处。