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肺切除术后胸膜脓胸的治疗优化

Treatment Optimization of Post-pneumonectomy Pleural Empyema.

作者信息

Petrov Danail B, Subotic Dragan, Yankov Georgi S, Valev Dinko G, Mekov Evgeni V

机构信息

Medical University - Sofia, Sofia, Bulgaria.

University Hospital Basel, Basel, Switzerland.

出版信息

Folia Med (Plovdiv). 2019 Dec 31;61(4):500-505. doi: 10.3897/folmed.61.e47943.

Abstract

INTRODUCTION

Pleural empyema after pneumonectomy still poses a serious postoperative complication. A bronchopleural fistula is often detected. Despite various therapeutic options developed during the last five decades it remains a major surgical challenge.

RESULTS

There is no widely accepted treatment for post-pneumonectomy pleural empyema (PPE) and the management depends mostly on the presence or absence of broncho-pleural fistula (BPF) and the patient’s general condition. In the absence of BPF, the role of surgery is still not clear because of its high morbidity and impossibility to prevent recurrences. In the earlier period, the definitive treatment consisted of open window thoracostomy followed by obliteration of the pleural cavity with antibiotic solution at the time of chest wall closure. Subsequently, the proposed different methods and modifications improved the outcome. There is an association between hospital volume and operative mortality after the lung resection. Hospital volume and the surgeon’s specialty have more influence on the outcome than the individual surgeon’s volume.

CONCLUSIONS

Treatment management of PPE should be individualized. Definitive treatment options comprise aggressive surgery that is not possible in quite a high proportion of impaired patients. Hospital volume, surgeon’s volume and surgeon’s specialty may influence the prognosis.

摘要

引言

肺切除术后的脓胸仍是一种严重的术后并发症。常可检测到支气管胸膜瘘。尽管在过去五十年中开发了各种治疗选择,但它仍然是一项重大的外科挑战。

结果

对于肺切除术后脓胸(PPE),目前尚无广泛接受的治疗方法,其管理主要取决于支气管胸膜瘘(BPF)的存在与否以及患者的一般状况。在没有BPF的情况下,手术的作用仍不明确,因为其发病率高且无法预防复发。在早期,确定性治疗包括开胸开窗引流术,随后在关闭胸壁时用抗生素溶液闭塞胸膜腔。随后,提出的不同方法和改进提高了治疗效果。肺切除术后的医院规模与手术死亡率之间存在关联。医院规模和外科医生的专业比单个外科医生的手术量对治疗效果的影响更大。

结论

PPE的治疗管理应个体化。确定性治疗选择包括积极的手术,但相当一部分受损患者无法进行这种手术。医院规模、外科医生的手术量和外科医生的专业可能会影响预后。

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