Department of Chemistry, University of Tennessee, Knoxville, Tennessee 37996, United States.
J Phys Chem A. 2020 May 21;124(20):4160-4170. doi: 10.1021/acs.jpca.9b12046. Epub 2020 May 7.
Microreactors have garnered widespread attention for their tunability and precise control of synthetic parameters to efficiently produce target species. Despite associated advances, a lack of online detection and optimization methods has stalled the progression of microfluidic reactors. Here we employ and characterize a total internal reflection transient absorption microscopy (TIRTAM) instrument to image excited state dynamics on a continuous flow device. The experiments presented demonstrate the capability to discriminate between different chromophores as well as in differentiating the effects of local chemical environments that a chromophore experiences. This work presents the first such online transient absorption measurements and provides a new direction for the advancement and optimization of chemical reactions in microfluidic devices.
微反应器因其可调性和对合成参数的精确控制而受到广泛关注，可有效地生产目标物种。尽管取得了相关进展，但缺乏在线检测和优化方法阻碍了微流控反应器的发展。在这里，我们采用并表征了全内反射瞬态吸收显微镜（TIRTAM）仪器，以在连续流动装置上成像激发态动力学。所呈现的实验证明了区分不同发色团以及区分发色团所经历的局部化学环境影响的能力。这项工作首次进行了这种在线瞬态吸收测量，并为微流控装置中化学反应的改进和优化提供了新的方向。
