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移植到新生大鼠体内的海马神经元建立了传出连合连接。

Hippocampal neurons grafted to newborn rats establish efferent commissural connections.

作者信息

Tønder N, Sørensen J C, Bakkum E, Danielsen E, Zimmer J

机构信息

Department of Neurobiology, University of Aarhus, Denmark.

出版信息

Exp Brain Res. 1988;72(3):577-83. doi: 10.1007/BF00250602.

DOI:10.1007/BF00250602
PMID:3234503
Abstract

The formation of commissural projections from developing rat hippocampal neurons grafted to the hippocampus of newborn littermates was examined by retrograde axonal transport of the fluorescent dye Fluorogold (FG). At six weeks of age the recipients received two injections of FG in the hippocampus contralateral to the graft. This resulted in labelling of normal, commissurally projecting neurons in the dentate hilus and CA3 of the host hippocampus. Neurons in several transplants were also labelled, and based on morphology and location they were identified as CA3 and dentate hilus neurons.

摘要

通过荧光染料氟金(FG)的逆行轴突运输,研究了移植到新生同窝仔鼠海马体中的发育中大鼠海马神经元连合投射的形成。在六周龄时,受体在移植对侧的海马体中接受了两次FG注射。这导致宿主海马齿状回门区和CA3区中正常的、具有连合投射的神经元被标记。几个移植物中的神经元也被标记,根据形态和位置,它们被鉴定为CA3和齿状回门区神经元。

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引用本文的文献

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本文引用的文献

1
Estimation of nuclear population from microtome sections.从切片估计核数量。
Anat Rec. 1946 Feb;94:239-47. doi: 10.1002/ar.1090940210.
2
Commissural connections of the hippocampal region in the rat, with special reference to their mode of termination.大鼠海马区的连合连接,特别涉及其终止方式。
J Comp Neurol. 1956 Oct;105(3):417-537. doi: 10.1002/cne.901050305.
3
Associational and commissural collaterals of neurons in the hippocampal formation (hilus fasciae dentatae and subfield CA3).海马结构(齿状回门和CA3亚区)中神经元的联合侧支和连合侧支。
移植到缺血性损伤海马体中的海马神经元:存活、成熟和整合的解剖学评估
Exp Brain Res. 1991;86(2):233-47. doi: 10.1007/BF00228948.
Brain Res. 1981 May 18;212(2):287-300. doi: 10.1016/0006-8993(81)90463-7.
4
Transplantation of central nervous tissue. An introduction with results and implications.中枢神经组织移植。结果与影响介绍。
Acta Neurol Scand. 1981 May;63(5):323-35.
5
Cellular, histochemical and connective organization of the hippocampus and fascia dentata transplanted to different regions of immature and adult rat brains.移植到未成熟和成年大鼠大脑不同区域的海马体和齿状回的细胞、组织化学和结缔组织结构
Brain Res. 1983 Jun;284(2-3):165-91. doi: 10.1016/0165-3806(83)90003-2.
6
Mossy fibre projections into and out of hippocampal transplants.苔藓纤维向海马移植体内部及外部的投射。
Neuroscience. 1983 Aug;9(4):783-801. doi: 10.1016/0306-4522(83)90267-1.
7
Neuropeptides and astroglia in intracerebral hippocampal transplants: an immunohistochemical study in the rat.脑内海马移植中的神经肽与星形胶质细胞:大鼠的免疫组织化学研究
J Comp Neurol. 1984 Aug 10;227(3):331-47. doi: 10.1002/cne.902270304.
8
Brain grafts can restore irradiation-damaged neuronal connections in newborn rats.脑移植可以恢复新生大鼠中受辐射损伤的神经元连接。
Nature. 1984;310(5972):51-3. doi: 10.1038/310051a0.
9
Connections made by transplants to the cerebral cortex of rat brains damaged in utero.移植到子宫内受损大鼠大脑皮质的连接情况。
J Neurosci. 1984 Jan;4(1):141-50. doi: 10.1523/JNEUROSCI.04-01-00141.1984.
10
Evidence for collateral projections by neurons in Ammon's horn, the dentate gyrus, and the subiculum: a multiple retrograde labeling study in the rat.海马角、齿状回和海马下托中神经元的侧支投射证据:大鼠的多重逆行标记研究
J Neurosci. 1981 May;1(5):548-59. doi: 10.1523/JNEUROSCI.01-05-00548.1981.