胰腺混合性神经内分泌-非神经内分泌肿瘤（MiNEN）：一种罕见的实体，值得注意。
Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN) of pancreas: a rare entity-worth to note.
机构信息
Pathology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Surgical Gastroenterology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
出版信息
BMJ Case Rep. 2020 Apr 27;13(4):e234855. doi: 10.1136/bcr-2020-234855.
Abstract
Mixed adenocarcinoma with neuroendocrine tumour of pancreas has been reported infrequently and consists of both epithelial and neuroendocrine component. We encountered an 81-year-old male patient who presented with clinical features of painful progressive jaundice for 1 month. Contrast-enhanced CT abdomen reported a mass in the pancreatic head with dilated common bile duct and pancreatic duct. He underwent pancreatoduodenectomy and histopathological examination revealed two different tumours: ductal adenocarcinoma admixed with neuroendocrine tumour of pancreas. He received adjuvant chemotherapy, and at the end of 1-year follow-up, he has no recurrence. Here, we reported this rare malignancy of pancreas for which pancreatoduodenectomy was done and diagnosed on histopathology with immunohistochemistry.
摘要
胰腺混合性腺神经内分泌癌较为罕见，由上皮和神经内分泌成分组成。我们遇到一位 81 岁男性患者，表现为进行性黄疸伴疼痛 1 个月。腹部增强 CT 报告胰头部肿块，伴有胆总管和胰管扩张。患者接受了胰十二指肠切除术，组织病理学检查显示两种不同的肿瘤：导管腺癌伴胰腺神经内分泌癌。患者接受了辅助化疗，在 1 年随访结束时，没有复发。在此，我们报告了这种罕见的胰腺恶性肿瘤，通过胰十二指肠切除术和免疫组织化学进行了病理诊断。
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