Pathology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Surgical Gastroenterology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
BMJ Case Rep. 2020 Apr 27;13(4):e234855. doi: 10.1136/bcr-2020-234855.
Mixed adenocarcinoma with neuroendocrine tumour of pancreas has been reported infrequently and consists of both epithelial and neuroendocrine component. We encountered an 81-year-old male patient who presented with clinical features of painful progressive jaundice for 1 month. Contrast-enhanced CT abdomen reported a mass in the pancreatic head with dilated common bile duct and pancreatic duct. He underwent pancreatoduodenectomy and histopathological examination revealed two different tumours: ductal adenocarcinoma admixed with neuroendocrine tumour of pancreas. He received adjuvant chemotherapy, and at the end of 1-year follow-up, he has no recurrence. Here, we reported this rare malignancy of pancreas for which pancreatoduodenectomy was done and diagnosed on histopathology with immunohistochemistry.
胰腺混合性腺神经内分泌癌较为罕见，由上皮和神经内分泌成分组成。我们遇到一位 81 岁男性患者，表现为进行性黄疸伴疼痛 1 个月。腹部增强 CT 报告胰头部肿块，伴有胆总管和胰管扩张。患者接受了胰十二指肠切除术，组织病理学检查显示两种不同的肿瘤：导管腺癌伴胰腺神经内分泌癌。患者接受了辅助化疗，在 1 年随访结束时，没有复发。在此，我们报告了这种罕见的胰腺恶性肿瘤，通过胰十二指肠切除术和免疫组织化学进行了病理诊断。
