活性药物代谢产物对血浆浓度-效应相关性的影响。 - Suppr

Suppr

超能文献

Effect of active drug metabolites on plasma level-response correlations.

作者信息

Atkinson A J, Strong J M

出版信息

J Pharmacokinet Biopharm. 1977 Apr;5(2):95-109. doi: 10.1007/BF01066214.

DOI:10.1007/BF01066214

PMID:323459

Abstract

摘要

相似文献

Effect of active drug metabolites on plasma level-response correlations.活性药物代谢产物对血浆浓度-效应相关性的影响。

J Pharmacokinet Biopharm. 1977 Apr;5(2):95-109. doi: 10.1007/BF01066214.

Impact of active metabolites on monitoring plasma concentrations of therapeutic drugs.

Ther Drug Monit. 1980;2(1):19-27. doi: 10.1097/00007691-198001000-00004.

Measurement of therapeutic agents in blood.血液中治疗药物的测量。

Adv Clin Chem. 1973;16:47-109. doi: 10.1016/s0065-2423(08)60344-3.

Determination of plasma procainamide and N-acetylprocainamide concentration by high-pressure liquid chromatography.采用高压液相色谱法测定血浆普鲁卡因胺和N-乙酰普鲁卡因胺浓度。

Clin Chem. 1977 Jul;23(7):1318-20.

The pharmacology of cardio-active agents.

Cardiovasc Clin. 1972;4(3):103-18.

Glutethimide and 4-OH glutethimide: pharmacokinetics and effect on performance in man.

Clin Pharmacol Ther. 1977 Oct;22(4):458-64. doi: 10.1002/cpt1977224458.

Arterial-venous plasma concentration differences of six drugs in the dog and rabbit after intravenous administration.

Res Commun Chem Pathol Pharmacol. 1981 Apr;32(1):27-39.

Pharmacodynamic and pharmacokinetic measurements in cardiovascular-renal drugs.

Clin Pharmacol Ther. 1974 Jul;16(1):201-11. doi: 10.1002/cpt1974161part2201.

Letter: Limitations in the use of hydrolytic rate constants for the simultaneous determination of drug and metabolite in serum.信函：水解速率常数在血清中药物与代谢物同时测定中的应用局限性。

Biochem Med. 1974 Feb;9(2):190-2. doi: 10.1016/0006-2944(74)90052-0.

Clinical pharmacokinetics of procainamide.普鲁卡因胺的临床药代动力学。

Clin Pharmacokinet. 1978 Mar-Apr;3(2):97-107. doi: 10.2165/00003088-197803020-00001.

引用本文的文献

Pharmacokinetics of lidocaine and its deethylated metabolite: dose and time dependency studies in man.利多卡因及其脱乙基代谢物的药代动力学：人体剂量和时间依赖性研究

J Pharmacokinet Biopharm. 1982 Jun;10(3):265-81. doi: 10.1007/BF01059261.

Significance of acetylator phenotype in pharmacokinetics and adverse effects of procainamide.乙酰化代谢表型在普鲁卡因胺药代动力学及不良反应中的意义

Eur J Clin Pharmacol. 1983;25(6):791-5. doi: 10.1007/BF00542522.

The relationship between serum concentrations and central nervous system actions of metoprolol.美托洛尔的血清浓度与中枢神经系统作用之间的关系。

J Neurol Neurosurg Psychiatry. 1985 Feb;48(2):101-6. doi: 10.1136/jnnp.48.2.101.

A review of metabolite kinetics.代谢物动力学综述。

J Pharmacokinet Biopharm. 1985 Dec;13(6):633-62. doi: 10.1007/BF01058905.

Effect of a diffusional barrier to a metabolite across hepatocytes on its kinetics in "enzyme-distributed" models: a computer-aided simulation study.

J Pharmacokinet Biopharm. 1987 Aug;15(4):399-421. doi: 10.1007/BF01066521.

Formation of active metabolites of psychotropic drugs. An updated review of their significance.精神药物活性代谢产物的形成。对其重要性的最新综述。

Clin Pharmacokinet. 1990 Jun;18(6):434-59. doi: 10.2165/00003088-199018060-00002.

Acebutolol in hypertension: relationships between drug concentration and effects.

Eur J Clin Pharmacol. 1978 Dec 18;14(6):383-90. doi: 10.1007/BF00716378.

本文引用的文献

Acetylation of procaine amide in man studied with a new gas chromatographic method.用一种新的气相色谱法研究人体中普鲁卡因酰胺的乙酰化。

Br J Clin Pharmacol. 1974 Dec;1(6):467-75. doi: 10.1111/j.1365-2125.1974.tb01696.x.

A simplified method of evaluating dose-effect experiments.一种评估剂量效应实验的简化方法。

J Pharmacol Exp Ther. 1949 Jun;96(2):99-113.

Use of pronestyl in the treatment of ectopic rhythms; treatment of 98 episodes in 78 patients.普鲁卡因酰胺用于异位心律的治疗；治疗78例患者的98次发作。

Am J Med. 1951 Oct;11(4):431-41. doi: 10.1016/0002-9343(51)90178-7.

The anticonvulsant activity of o-phenyl succinimides.邻苯基琥珀酰亚胺的抗惊厥活性。

J Pharmacol Exp Ther. 1951 Sep;103(1):54-61.

The use of procaine amide in cardiac arrhythmias.普鲁卡因酰胺在心律失常中的应用。

Circulation. 1951 Jul;4(1):13-22. doi: 10.1161/01.cir.4.1.13.

N-methylated derivatives of barbituric acid, hydantoin and oxazolidinedione used in the treatment of epilepsy.用于治疗癫痫的巴比妥酸、乙内酰脲和恶唑烷二酮的N-甲基化衍生物。

Neurology. 1958 Apr;8(Suppl 1):106-12. doi: 10.1212/wnl.8.suppl_1.106.

New drugs in the treatment of petit mal epilepsy.

Am J Psychiatry. 1953 Apr;109(10):767-73. doi: 10.1176/ajp.109.10.767.

Multicompartment pharmacokinetic models and pharmacologic effects.多房室药代动力学模型与药理效应。

J Pharm Sci. 1969 Apr;58(4):422-4. doi: 10.1002/jps.2600580406.

Local anesthetic drug-induced seizures in rhesus monkeys.

Anesth Analg. 1970 Nov-Dec;49(6):986-97.

Mechanism of convulsions elicited by local anesthetic agents. I. Local anesthetic depression of electrically-induced seizures in man.

Anesth Analg. 1970 May-Jun;49(3):504-10.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验