远端小肠切除术会增加大肠的黏膜通透性。
Distal small bowel resection increases mucosal permeability in the large intestine.
作者信息
Vázquez C M, Molina M T, Ilundain A
机构信息
Departamento de Fisiología Animal, Facultad de Farmacia, Universidad de Sevilla, España.
出版信息
Digestion. 1988;40(3):168-72. doi: 10.1159/000199651.
Intestinal 14C-erythritol clearance, as a measure of mucosal permeability, was evaluated in rats 4 weeks after distal small bowel resection. In the cecum and colon of resected animals, erythritol clearance was increased both per organ and per unit tissue mass, regardless of the extent of the resection. In the remnant jejunum, however, a small but significant increase in erythritol clearance was only observed after 80% distal small bowel resection, no matter which reference was chosen. This is the first demonstration that intestinal resection increases the mucosal permeability of the remnant small and large intestine.
作为粘膜通透性的一项指标，在大鼠远端小肠切除术后4周评估肠道14C-赤藓醇清除率。在切除动物的盲肠和结肠中，无论切除范围如何，每个器官和每单位组织质量的赤藓醇清除率均升高。然而，在残余空肠中，无论选择何种参照，仅在80%远端小肠切除术后才观察到赤藓醇清除率有小幅但显著的升高。这是首次证明肠道切除会增加残余小肠和大肠的粘膜通透性。
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