College of Medicine, Burrell College of Osteopathic Medicine, Las Cruces, NM.
Department of Economics, Applied Statistics, and International Business, New Mexico State University, Las Cruces, NM.
Ethn Dis. 2020 Apr 23;30(2):357-364. doi: 10.18865/ed.30.2.357. eCollection 2020 Spring.
To examine incidence and survival of testicular cancer in New Mexico, overall and separately for border and non-border counties.
Incidence and 5-year survival rates for testicular cancer were obtained from the SEER18 database using the SEER*Stat program following established NCI protocols. Incidence data were compared using Student's t-test. Age-adjusted 5-year survival and Kaplan-Meier method were used to estimate survival. Log-rank tests were used to compare survival for New Mexico to the remaining17 geographical areas of the SEER 18 and for the New Mexico border counties to the New Mexico non-border counties. Odds ratios were used to compare testicular stage at diagnosis. Cox proportional hazards regression was performed to account for race/ethnicity, and border status.
From 2000-2015, New Mexico had a testicular cancer incidence rate of 6.3 per 100,000 people, significantly higher than SEER18 (P<.001). The 5-year survival rate in New Mexico did not differ significantly from the SEER18 (P=.3). Border Hispanics had a lower survival rate than border non-Hispanic populations (P=.03). From 2000-2018, New Mexico had a significantly higher proportion of distant cancers than the SEER18 (OR: 1.29, 95% CI: 1.08 to 1.53, P=.005).
The higher incidence of testicular cancer in New Mexico does not appear to have a clear explanation based on the current understanding of risk factors; however, the increased incidence in New Mexico does not appear to be associated with increased mortality. The higher proportion of advanced testicular cancers in New Mexico may represent a delay in diagnosis. The increased mortality rate seen in Hispanic border populations may be due in part to barriers to care.
检查新墨西哥州睾丸癌的发病率和生存率，总体上和分别对边境和非边境县进行检查。
使用 SEER*Stat 程序通过 SEER18 数据库获得睾丸癌的发病率和 5 年生存率，遵循 NCI 既定协议。使用学生 t 检验比较发病率数据。使用年龄调整的 5 年生存率和 Kaplan-Meier 方法估计生存率。对数秩检验用于比较新墨西哥州与 SEER18 的其余 17 个地理区域以及新墨西哥州边境县与非边境县的生存率。比值比用于比较诊断时的睾丸分期。使用 Cox 比例风险回归来解释种族/民族和边境地位。
从 2000 年到 2015 年，新墨西哥州的睾丸癌发病率为每 10 万人 6.3 例，明显高于 SEER18（P<.001）。新墨西哥州的 5 年生存率与 SEER18 无显著差异（P=.3）。边境西班牙裔的生存率低于边境非西班牙裔人口（P=.03）。从 2000 年到 2018 年，新墨西哥州的远处癌症比例明显高于 SEER18（OR：1.29，95%CI：1.08 至 1.53，P=.005）。
根据目前对危险因素的理解，新墨西哥州睾丸癌发病率的增加似乎没有明确的解释；然而，新墨西哥州发病率的增加似乎与死亡率的增加无关。新墨西哥州晚期睾丸癌比例较高可能表明诊断延迟。西班牙裔边境人口死亡率的增加可能部分归因于获得医疗保健的障碍。
