Cancer Epidemiology Services, New Jersey Department of Health, Trenton, NJ 08625, USA.
Cancer Med. 2013 Jun;2(3):403-11. doi: 10.1002/cam4.84. Epub 2013 May 8.
Previous studies found that uninsured and Medicaid insured cancer patients have poorer outcomes than cancer patients with private insurance. We examined the association between health insurance status and survival of New Jersey patients 18-64 diagnosed with seven common cancers during 1999-2004. Hazard ratios (HRs) with 95% confidence intervals for 5-year cause-specific survival were calculated from Cox proportional hazards regression models; health insurance status was the primary predictor with adjustment for other significant factors in univariate chi-square or Kaplan-Meier survival log-rank tests. Two diagnosis periods by health insurance status were compared using Kaplan-Meier survival log-rank tests. For breast, colorectal, lung, non-Hodgkin lymphoma (NHL), and prostate cancer, uninsured and Medicaid insured patients had significantly higher risks of death than privately insured patients. For bladder cancer, uninsured patients had a significantly higher risk of death than privately insured patients. Survival improved between the two diagnosis periods for privately insured patients with breast, colorectal, or lung cancer and NHL, for Medicaid insured patients with NHL, and not at all for uninsured patients. Survival from cancer appears to be related to a complex set of demographic and clinical factors of which insurance status is a part. While ensuring that everyone has adequate health insurance is an important step, additional measures must be taken to address cancer survival disparities.
先前的研究发现,没有保险和拥有医疗补助保险的癌症患者比拥有私人保险的癌症患者预后更差。我们研究了新泽西州在 1999 年至 2004 年间被诊断出患有七种常见癌症的 18-64 岁患者的健康保险状况与生存之间的关系。通过 Cox 比例风险回归模型计算出 5 年特定原因生存率的风险比(HRs)及其 95%置信区间;健康保险状况是主要预测因子,在单变量卡方检验或 Kaplan-Meier 生存对数秩检验中对其他重要因素进行了调整。通过 Kaplan-Meier 生存对数秩检验比较了两个诊断期的健康保险状况。对于乳腺癌、结直肠癌、肺癌、非霍奇金淋巴瘤(NHL)和前列腺癌,未参保和享受医疗补助保险的患者的死亡风险明显高于私人保险患者。对于膀胱癌,未参保患者的死亡风险明显高于私人保险患者。对于乳腺癌、结直肠癌或肺癌和 NHL 的私人保险患者、NHL 的医疗补助保险患者,生存状况在两个诊断期之间有所改善,而未参保患者的生存状况则完全没有改善。癌症的生存状况似乎与一系列复杂的人口统计学和临床因素有关,其中保险状况是其中的一部分。尽管确保每个人都有足够的健康保险是一个重要步骤,但还必须采取其他措施来解决癌症生存差异问题。