Greenberger P A, Patterson R
Department of Medicine, Northwestern University Medical School, Chicago, Illinois 60611.
Allergy Proc. 1988 Sep-Oct;9(5):539-43. doi: 10.2500/108854188778965555.
Eighty pregnancies in 73 gravidas with severe asthma who required inhaled and/or systemic corticosteroids were reported in an attempt to define the effects of asthma and its treatment on the outcome of pregnancy. No maternal deaths occurred. Infants delivered from gravidas who experienced at least one episode of status asthmaticus during gestation had decreased birth weights (p = 0.03) compared with infants delivered from gravidas who did not require emergency therapy or develop status asthmaticus. The data confirm the importance of maintaining gravidas with severe asthma as free from symptoms and signs of asthma as possible.
为了确定哮喘及其治疗对妊娠结局的影响，对73例需要吸入和/或全身使用皮质类固醇的重度哮喘孕妇的80次妊娠进行了报道。未发生孕产妇死亡。与未接受紧急治疗或未发生哮喘持续状态的孕妇所分娩的婴儿相比，在妊娠期经历至少一次哮喘持续状态发作的孕妇所分娩的婴儿出生体重降低（p = 0.03）。数据证实了使重度哮喘孕妇尽可能摆脱哮喘症状和体征的重要性。
