Cardiovascular Division and Center for Resuscitation Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
Medical Faculty, University of Ljubljana.
Curr Opin Crit Care. 2020 Jun;26(3):228-235. doi: 10.1097/MCC.0000000000000717.
Extracorporeal cardiopulmonary resuscitation (ECPR) is a contemporary resuscitation approach that employs veno-arterial extracorporeal membrane oxygenation (VA-ECMO). This approach is increasingly used worldwide to mitigate the widespread hemodynamic and multiorgan dysfunction that accompanies cardiac arrest.
In this review, the physiology of VA-ECMO and ECPR, the role of ECPR in contemporary resuscitation care, the complications associated with ECPR and VA-ECMO usage, and intensive care considerations for this population are discussed.
ECPR offers a promising mechanism to mitigate multiorgan injury and allow time for the institution of supportive interventions required to effectively treat cardiac arrest. More prospective data in the context of extensive prehospital and hospital collaboration is needed to promote its successful use.
体外心肺复苏(ECPR)是一种采用静脉-动脉体外膜肺氧合(VA-ECMO)的现代复苏方法。这种方法在全球范围内越来越多地被用于减轻伴随心脏骤停的广泛的血流动力学和多器官功能障碍。
在这篇综述中,讨论了 VA-ECMO 和 ECPR 的生理学、ECPR 在当代复苏护理中的作用、ECPR 和 VA-ECMO 使用相关的并发症,以及对该人群的重症监护考虑。
ECPR 提供了一种有前途的机制,可以减轻多器官损伤,并为实施有效治疗心脏骤停所需的支持性干预措施留出时间。需要在广泛的院前和院内协作的背景下进行更多的前瞻性数据研究,以促进其成功应用。