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一株嗜水气单胞菌引起慢性眼内炎 1 例报告

A CASE REPORT OF CHRONIC ENDOPHTHALMITIS SECONDARY TO AQUAMICROBIUMterrae.

机构信息

Cleveland Clinic Foundation, Cole Eye Institute, Cleveland, Ohio.

出版信息

Retin Cases Brief Rep. 2022 Jul 1;16(4):448-451. doi: 10.1097/ICB.0000000000001003. Epub 2020 Apr 28.

DOI:10.1097/ICB.0000000000001003
PMID:32349062
Abstract

PURPOSE

Chronic postoperative endophthalmitis is a known complication of cataract surgery. Here, we report a case of chronic endophthalmitis following uncomplicated cataract surgery secondary to the atypical bacterium Aquamicrobium terrae .

METHODS

Retrospective case report of a single patient with endophthalmitis secondary to A. terrae.

RESULTS

A 61-year-old healthy patient presented with recurrent iridocyclitis following uncomplicated cataract surgery. Repeated attempts to taper off topical steroid eyedrops were unsuccessful. Anterior chamber paracentesis cultures and vitrectomy cultures grew the same gram-negative bacillus, A. terrae , on six different occasions. The patient was treated initially with a series of intravitreal ceftazidime injections and adjuvant oral minocycline with recurrence of inflammation necessitating pars plana vitrectomy with intraocular lens removal and total capsulectomy. Inflammatory episodes recurred until residual capsule fragments were ablated using endoscopic vitrectomy. Since ablation over 18 months ago, no further recurrences have occurred and the patient has excellent visual outcome.

CONCLUSION

A. terrae is a gram-negative bacillus recovered from polluted soil. This is the first case of postoperative endophthalmitis secondary to A. terrae and the first description of human infection caused by this newly identified microbe.

摘要

目的

慢性术后眼内炎是白内障手术后已知的并发症。在此,我们报告了一例由非典型细菌嗜水气单胞菌引起的单纯白内障手术后慢性眼内炎的病例。

方法

对 1 例嗜水气单胞菌性眼内炎患者进行回顾性病例报告。

结果

一名 61 岁健康患者在单纯白内障手术后出现复发性虹膜炎。多次试图减少局部皮质类固醇滴眼剂均未成功。前房房水穿刺培养和玻璃体切割培养在六次不同的情况下均培养出同一种革兰氏阴性杆菌,即嗜水气单胞菌。该患者最初接受了一系列玻璃体内头孢他啶注射和辅助口服米诺环素治疗,但炎症复发,需要进行玻璃体切除术,切除人工晶状体和全部囊袋。炎症反复发作,直至使用内镜玻璃体切除术切除残留的囊袋碎片。自 18 个月前消融以来,未再出现复发,患者视力恢复良好。

结论

嗜水气单胞菌是一种从污染土壤中分离出来的革兰氏阴性杆菌。这是首例由嗜水气单胞菌引起的术后眼内炎病例,也是首例由这种新鉴定的微生物引起的人类感染的描述。

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