Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, Japan.
Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Japan.
Intern Med. 2020 Aug 1;59(15):1879-1881. doi: 10.2169/internalmedicine.4457-20. Epub 2020 Apr 30.
An asymptomatic 47-year-old woman was admitted with pleural effusion and pulmonary infiltrates 1 month after ingesting raw wild boar and deer meat. Both her blood and pleural fluid were eosinophilic. Thoracoscopy revealed multiple nodules of the pleura, and biopsy samples of the nodules showed necrosis with epithelioid cell granulomas. An enzyme-linked immunosorbent assay was positive for antibodies against Paragonimus westermani, and the patient was successfully treated with praziquantel. This is the first reported case of pulmonary or pleuropulmonary paragonimiasis where several pleural nodules were observed. The detection of pleural nodules on thoracoscopy can contribute to the prompt and accurate diagnosis of paragonimiasis.
一名 47 岁无症状女性,在食用生野猪和鹿肉 1 个月后因胸腔积液和肺部浸润而入院。她的血液和胸腔积液均呈嗜酸性粒细胞增多。胸腔镜检查显示胸膜多发性结节,结节活检样本显示坏死伴上皮样细胞肉芽肿。酶联免疫吸附试验检测出对卫氏并殖吸虫的抗体呈阳性,患者成功接受了吡喹酮治疗。这是首例报道的肺部或胸膜并殖吸虫病病例,其中观察到多个胸膜结节。胸腔镜下胸膜结节的检测有助于及时准确地诊断并殖吸虫病。