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Brain-spleen connection aids antibody production.

作者信息

Cathomas Flurin, Russo Scott J

出版信息

Nature. 2020 May;581(7807):142-143. doi: 10.1038/d41586-020-01168-0.

DOI:10.1038/d41586-020-01168-0
PMID:32350424
Abstract
摘要

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Brain-spleen connection aids antibody production.脑-脾连接有助于抗体产生。
Nature. 2020 May;581(7807):142-143. doi: 10.1038/d41586-020-01168-0.
2
ANTAGONISTIC EFFECTS OF HUMORAL ISOANTIBODIES ON THE IN VITRO CYTOTOXICITY OF IMMUNE LYMPHOID CELLS.体液同种抗体对免疫淋巴细胞体外细胞毒性的拮抗作用。
J Exp Med. 1965 Jul 1;122(1):11-23. doi: 10.1084/jem.122.1.11.
3
A Brain-Spleen Axis Regulates Humoral Immunity.脑-脾轴调节体液免疫。
Neurosci Bull. 2021 Mar;37(3):427-429. doi: 10.1007/s12264-020-00610-7. Epub 2020 Nov 13.
4
Brain-spleen link tunes immunity.
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INHIBITION OF ANTIBODY PLAQUE FORMATION BY SENSITIZED LYMPHOID CELLS: RAPID INDICATOR OF TRANSPLANTATION IMMUNITY.致敏淋巴细胞对抗体斑块形成的抑制作用：移植免疫的快速指标。
Science. 1964 Aug 7;145(3632):607-9. doi: 10.1126/science.145.3632.607.
6
[Effect of leucomisine on cell and humoral immunity indices].
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[Regulatory role of bone marrow in immunogenesis. III. Humoral factors stimulating and suppressing antibody formation produced by bone marrow cells in in vitro cultures].[骨髓在免疫发生中的调节作用。III. 体外培养中刺激和抑制骨髓细胞产生抗体形成的体液因子]
Zh Mikrobiol Epidemiol Immunobiol. 1978 Jul(7):56-61.
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Attempt at a comparative evolutionary approach to the study of the mechanism of antibody formation. I. Study of humoral immunity factors in invertebrates.尝试采用比较进化方法研究抗体形成机制。一、无脊椎动物体液免疫因子的研究。
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IL-5 and IL-17A are critical for the chronic IgE response and differentiation of long-lived antibody-secreting cells in inflamed tissues.IL-5 和 IL-17A 对于慢性 IgE 应答以及在炎症组织中长寿命分泌抗体细胞的分化是至关重要的。
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Cellular and humoral immunity after allogeneic transplantation in the rat. 3. The effect of passive antibody on cellular and humoral immunity after allogeneic renal transplantation.大鼠同种异体移植后的细胞免疫和体液免疫。3. 被动抗体对同种异体肾移植后细胞免疫和体液免疫的影响。
Transplantation. 1973 Nov;16(5):432-40. doi: 10.1097/00007890-197311000-00007.

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Hypothalamic CRF neurons facilitate brain reward function.

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Neurobiology of Resilience: Interface Between Mind and Body.韧性的神经生物学：身心界面。
Biol Psychiatry. 2019 Sep 15;86(6):410-420. doi: 10.1016/j.biopsych.2019.04.011. Epub 2019 Apr 17.
2
A Quantitative Analysis of the Distribution of CRH Neurons in Whole Mouse Brain.小鼠全脑促肾上腺皮质激素释放激素神经元分布的定量分析
Front Neuroanat. 2017 Jul 25;11:63. doi: 10.3389/fnana.2017.00063. eCollection 2017.
3
It takes nerve to fight back: The significance of neural innervation of the bone marrow and spleen for immune function.
下丘脑 CRF 神经元促进大脑奖赏功能。
Curr Biol. 2024 Jan 22;34(2):389-402.e5. doi: 10.1016/j.cub.2023.12.046. Epub 2024 Jan 11.
4
Editorial: Human brain banking - Bridging brain health and precision neurology.社论：人类脑库——连接脑健康与精准神经病学
Front Neurol. 2023 Oct 27;14:1322200. doi: 10.3389/fneur.2023.1322200. eCollection 2023.
5
Comparison of peripheral blood T, B, and NK lymphocytes between frontline medical workers for treating patients of COVID-19 and normal outpatient and emergency medical workers in China.中国新冠肺炎救治一线医务工作者与普通门诊及急诊医务工作者外周血T、B和NK淋巴细胞的比较
Front Psychiatry. 2023 Apr 19;14:1165614. doi: 10.3389/fpsyt.2023.1165614. eCollection 2023.
6
Splenectomy does not affect mouse behaviors.脾切除术不影响小鼠的行为。
Neural Regen Res. 2023 Aug;18(8):1789-1794. doi: 10.4103/1673-5374.360247.
7
A novel built-in adjuvant metallothionein-3 aids protein antigens to induce rapid, robust, and durable immune responses.一种新型内源性佐剂金属硫蛋白 3 可辅助蛋白抗原诱导快速、强烈且持久的免疫应答。
Front Immunol. 2022 Nov 8;13:1024437. doi: 10.3389/fimmu.2022.1024437. eCollection 2022.
8
Enhanced Bacteremia in Dextran Sulfate-Induced Colitis in Splenectomy Mice Correlates with Gut Dysbiosis and LPS Tolerance.右旋糖酐硫酸酯诱导的脾切除小鼠结肠炎中增强的菌血症与肠道菌群失调和 LPS 耐受相关。
Int J Mol Sci. 2022 Jan 31;23(3):1676. doi: 10.3390/ijms23031676.
9
Abnormalities of the composition of the gut microbiota and short-chain fatty acids in mice after splenectomy.脾切除术后小鼠肠道微生物群和短链脂肪酸组成的异常。
Brain Behav Immun Health. 2021 Jan 4;11:100198. doi: 10.1016/j.bbih.2021.100198. eCollection 2021 Feb.
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Red light exaggerated sepsis-induced learning impairments and anxiety-like behaviors.红光加剧了脓毒症引起的学习障碍和类似焦虑的行为。
Aging (Albany NY). 2020 Nov 10;12(23):23739-23760. doi: 10.18632/aging.103940.
需要勇气才能反击：骨髓和脾脏的神经支配对免疫功能的意义。
Semin Cell Dev Biol. 2017 Jan;61:60-70. doi: 10.1016/j.semcdb.2016.08.010. Epub 2016 Aug 11.
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Activation of the reward system boosts innate and adaptive immunity.激活奖励系统可增强先天免疫和适应性免疫。
Nat Med. 2016 Aug;22(8):940-4. doi: 10.1038/nm.4133. Epub 2016 Jul 4.
5
The generation of antibody-secreting plasma cells.浆细胞分泌抗体的产生。
Nat Rev Immunol. 2015 Mar;15(3):160-71. doi: 10.1038/nri3795. Epub 2015 Feb 20.
6
Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit.乙酰胆碱合成 T 细胞在迷走神经回路中传递神经信号。
Science. 2011 Oct 7;334(6052):98-101. doi: 10.1126/science.1209985. Epub 2011 Sep 15.
7
The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights.糖皮质激素的抗炎和免疫抑制作用：最新进展和机制见解。
Mol Cell Endocrinol. 2011 Mar 15;335(1):2-13. doi: 10.1016/j.mce.2010.04.005. Epub 2010 Apr 14.
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The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress.下丘脑-垂体-肾上腺轴在应激神经内分泌反应中的作用。
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Structure and function of the spleen.脾脏的结构与功能。
Nat Rev Immunol. 2005 Aug;5(8):606-16. doi: 10.1038/nri1669.
10
The role of the amygdala in fear and anxiety.杏仁核在恐惧和焦虑中的作用。
Annu Rev Neurosci. 1992;15:353-75. doi: 10.1146/annurev.ne.15.030192.002033.