菲律宾人群中血清类黏蛋白和α-2-HS-糖蛋白的基因多态性

Genetic polymorphisms of orosomucoid and alpha-2-HS-glycoprotein in a Philippine population.

作者信息

Umetsu K, Yuasa I, Nishimura H, Sasaki H, Suzuki T

机构信息

Department of Forensic Medicine, Yamagata University School of Medicine, Japan.

出版信息

Hum Hered. 1988;38(5):287-90. doi: 10.1159/000153801.

DOI:10.1159/000153801

PMID:3235093

Abstract

A Philippine population was investigated for genetic polymorphism of orosomucoid 1 (ORM1), orosomucoid 2 (ORM2), and alpha-2-HS-glycoprotein (A2HS) by isoelectric focusing. The allele frequencies were: ORM11 = 0.7904, ORM12 = 0.1687, ORM12.1 = 0.0409, ORM21 = 1.0000; A2HS1 = 0.6870, A2HS2 = 0.3130. Compared with the Japanese population, the Philippine population has higher frequencies of ORM11 and A2HS2, and lower frequencies of ORM12.1 and A2HS1.

摘要

通过等电聚焦法对菲律宾人群的类粘蛋白1（ORM1）、类粘蛋白2（ORM2）和α-2-HS-糖蛋白（A2HS）的基因多态性进行了研究。等位基因频率分别为：ORM11 = 0.7904，ORM12 = 0.1687，ORM12.1 = 0.0409，ORM21 = 1.0000；A2HS1 = 0.6870，A2HS2 = 0.3130。与日本人群相比，菲律宾人群中ORM11和A2HS2的频率较高，而ORM12.1和A2HS1的频率较低。