Clayton J M, Hayes A C, Hammel J, Boyd W C, Hartford C E, Barnes R W
J Trauma. 1977 Apr;17(4):293-8. doi: 10.1097/00005373-197704000-00006.
Xe-133 washout determination of muscle blood flow (MBF) was used to detect muscle ischemia in electrical injury of an experimental animal model and three patients. The control MBF of rabbit hindlimbs, which averaged 11.29 +/- 1.07 cc/min/100 gm, was significantly reduced by electrical injury, to 5.82 +/- 1.49 cc/min/100 gm (p less than 0.001). An electrical injury of 4,000 watt-seconds or greater was associated with uniform MBF less than 1.00 cc/min/100 gm and with histopathologic alterations of muscle necrosis. Thenar MBF less than 1.00 cc/min/100 gm in two patients was associated with muscle necrosis requiring distal arm amputation. The remaining patient with sequential muscle blood flows above this level had uneventful healing of hand electrical injuries. Xe-133 determination of MBF may be a useful objective technique to determine the extent of electrical injury in muscle.
采用氙 - 133洗脱法测定肌肉血流量（MBF），以检测实验动物模型及3例患者电损伤后的肌肉缺血情况。兔后肢的对照MBF平均为11.29±1.07毫升/分钟/100克，电损伤后显著降低至5.82±1.49毫升/分钟/100克（p＜0.001）。4000瓦秒或更大强度的电损伤与MBF均匀低于1.00毫升/分钟/100克以及肌肉坏死的组织病理学改变相关。2例患者的大鱼际肌MBF低于1.00毫升/分钟/100克，与需要进行上臂远端截肢的肌肉坏死相关。另1例患者的连续肌肉血流量高于此水平，手部电损伤顺利愈合。氙 - 133测定MBF可能是一种有用的客观技术，可用于确定肌肉电损伤的程度。
