Pessina G P, Ciccoli L, Fanetti G
Istituto di Fisiologia Generale, Università, Siena.
Ital J Biochem. 1988 Sep-Oct;37(5):293-301.
We have studied the fatty acid composition of total lipids of erythrocytes and vesicles either during storage of human erythrocytes in their own plasma under blood bank conditions or during incubation at 37 degrees C in protein-free media. Vesicles appear as a heterogeneous population with a diameter of about 130 nm and a varying content of hemoglobin. The fatty acid pattern of vesicle total lipids changes in respect to control erythrocytes, while in erythrocytes it remains fairly constant during the total ageing period. Our results indicate a marked rearrangement of the membrane components during blood storage.
我们研究了在血库条件下人类红细胞在自身血浆中储存期间，以及在无蛋白培养基中于37℃孵育期间，红细胞和囊泡总脂质的脂肪酸组成。囊泡呈现为直径约130nm且血红蛋白含量各异的异质群体。与对照红细胞相比，囊泡总脂质的脂肪酸模式发生了变化，而红细胞在整个衰老期间其脂肪酸模式保持相当稳定。我们的结果表明，血液储存期间膜成分发生了显著重排。
