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[不同年龄大鼠红细胞膜脂质脂肪酸组成的变化]

[Variations in the fatty acid composition of rat erythrocyte membrane lipids at different ages].

作者信息

Ciccoli L, Fulceri R

出版信息

Boll Soc Ital Biol Sper. 1980 Oct 15;56(19):1982-8.

PMID:7459110
Abstract

The fatty acid composition of the erythrocyte lipids was studied in newborn, growing and adult rats. The percentage of oleic acid progressively decreased from the birth up to the adult age, while that of linoleic acid markedly increased. A smaller increase was also seen in the arachidonic acid content. These changes do not seem to be accounted for by differences in the percentages of the major phospholipid fractions or to differences in the age of the erythrocyte. Rather, variations in the fatty acid pattern of the various fractions of plasma lipids seem to be responsible for the lipid changes in the erythrocyte membrane.

摘要

对新生、生长中和成年大鼠的红细胞脂质的脂肪酸组成进行了研究。从出生到成年,油酸的百分比逐渐下降,而亚油酸的百分比则显著增加。花生四烯酸含量也有较小幅度的增加。这些变化似乎不能用主要磷脂组分百分比的差异或红细胞年龄的差异来解释。相反,血浆脂质各组分脂肪酸模式的变化似乎是红细胞膜脂质变化的原因。

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