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[耳蜗过程在产生朱厄特IV和V脑干电位成分中的作用]

[Effect of cochlear processes in generating Jewett IV and V brain stem potential components].

作者信息

Janssen T, Böhnke F, Steinhoff H J

机构信息

Universitäts-HNO-Klinik und Poliklinik rechts der Isar (TU) München.

出版信息

HNO. 1988 Dec;36(12):511-5.

PMID:3235366
Abstract

Polarity of the stimulus influences latency, amplitude and waveform of the human auditory brainstem response (ABR). One clear feature is the splitting of the wave complex JIV and JV in separate peaks following rarefaction stimulation. ABR was recorded using high-pass filtering to mask the basilar membrane partially to establish whether and to what extent basal hair cells contribute to waves IV and V. Wave IV disappeared in response to rarefaction stimuli with masking of the basal region. In contrast, wave V appeared with reduced amplitude and delayed latency in response to condensation stimuli. A model was developed to determine the motion of the basilar membrane and the distribution over time of the action potential on the auditory nerve fibers following rarefaction and condensation stimuli. The rarefaction stimulus produces a bifid and the condensation stimulus only a single-peaked contribution. It is suggested that the splitting of the wave complex IV and V may be traced to mechanical processing in the cochlea.

摘要

刺激的极性会影响人类听觉脑干反应(ABR)的潜伏期、波幅和波形。一个明显的特征是,在稀疏刺激后,复合波JIV和JV会分裂成单独的峰。使用高通滤波记录ABR,以部分掩盖基底膜,从而确定基底毛细胞是否以及在何种程度上对波IV和波V有贡献。在基底区域被掩盖的情况下,对稀疏刺激的反应中,波IV消失。相反,对密集刺激的反应中,波V出现,但其波幅降低且潜伏期延迟。开发了一个模型来确定在稀疏和密集刺激后基底膜的运动以及听觉神经纤维上动作电位随时间的分布。稀疏刺激产生双峰,而密集刺激仅产生单峰贡献。有人认为,复合波IV和V的分裂可能追溯到耳蜗中的机械加工过程。

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