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酒精性昏迷在青年人群抑郁症状中的作用。

The role of alcohol-induced blackouts in symptoms of depression among young adults.

机构信息

Department of Psychiatry, University of Missouri School of Medicine, 1 Hospital Dr DC067.00, Columbia, MO 65212, USA; Center for Alcohol and Addiction Studies, Department of Behavioral and Social Sciences, Brown University School of Public Health, Box G-S121-5, Providence, RI 02912, USA.

Department of Psychology, City University of New York, Brooklyn College, 2900 Bedford Ave, Brooklyn, NY 11210, USA; Center for Alcohol and Addiction Studies, Department of Behavioral and Social Sciences, Brown University School of Public Health, Box G-S121-5, Providence, RI 02912, USA.

出版信息

Drug Alcohol Depend. 2020 Jun 1;211:108027. doi: 10.1016/j.drugalcdep.2020.108027. Epub 2020 Apr 23.

Abstract

OBJECTIVE

Blackouts are associated with other alcohol-related consequences and depression among young adults, but the mechanisms underlying these associations are unclear. Using two separate samples, we tested the hypothesis that blackouts would be linked to symptoms of depression due in part to their association with other alcohol-related consequences.

METHOD

Young adults who use alcohol completed assessments at baseline in Sample 1 (N = 381, 58% female) and baseline, 3 months, and 6 months in Sample 2 (N = 603, 53 % female). Bootstrapped confidence intervals were used to examine the direct and indirect effects of blackouts on depressive symptoms, using cross-sectional mediation analysis in Sample 1 and a counterfactual approach with longitudinal data in Sample 2.

RESULTS

In both samples, alcohol-induced blackouts were associated with alcohol-related consequences, which in turn were associated with symptoms of depression. In Sample 1, blackouts had both direct and indirect (mediated) effects on depressive symptoms. In Sample 2, blackouts measured at baseline only had an indirect effect on depressive symptoms six months later through other alcohol-related consequences at three months.

CONCLUSIONS

Among heavy-drinking college students, the majority of whom reported minimal symptoms of depression, blackouts were associated with increases in other alcohol-related consequences, which in turn were associated with increases in symptoms of depression. These findings suggest that prevention and intervention efforts targeting blackouts may help reduce other alcohol-related consequences among young adults.

摘要

目的

断片与年轻人的其他酒精相关后果和抑郁有关,但这些关联的机制尚不清楚。使用两个独立的样本,我们检验了这样一个假设,即断片会因与其他酒精相关后果的关联而与抑郁症状有关。

方法

在样本 1(N=381,58%女性)和样本 2(N=603,53%女性)的基线、3 个月和 6 个月时,使用酒精的年轻人完成了基线评估。使用 bootstrap 置信区间,通过横截面中介分析在样本 1 中检验断片对抑郁症状的直接和间接影响,在样本 2 中使用纵向数据的反事实方法检验间接影响。

结果

在两个样本中,酒精引起的断片与酒精相关的后果有关,而这些后果又与抑郁症状有关。在样本 1 中,断片对抑郁症状既有直接影响,也有间接(中介)影响。在样本 2 中,仅在基线测量的断片在三个月后通过其他与酒精相关的后果对六个月后的抑郁症状产生间接影响。

结论

在大量饮酒的大学生中,大多数人报告有轻微的抑郁症状,断片与其他与酒精相关的后果的增加有关,而这些后果又与抑郁症状的增加有关。这些发现表明,针对断片的预防和干预措施可能有助于减少年轻人的其他与酒精相关的后果。

相似文献

1
The role of alcohol-induced blackouts in symptoms of depression among young adults.酒精性昏迷在青年人群抑郁症状中的作用。
Drug Alcohol Depend. 2020 Jun 1;211:108027. doi: 10.1016/j.drugalcdep.2020.108027. Epub 2020 Apr 23.

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