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ASPIRE-3-PREVENT:英国冠心病事件后预防保健的横断面调查。

ASPIRE-3-PREVENT: a cross-sectional survey of preventive care after a coronary event across the UK.

作者信息

Jennings Catriona S, Kotseva Kornelia, Bassett Paul, Adamska Agnieszka, Wood David

机构信息

NHLI, Imperial College London, London, UK

National Institute for Prevention and Cardiovascular Health, National University of Ireland Galway, Galway, Ireland.

出版信息

Open Heart. 2020 Apr;7(1). doi: 10.1136/openhrt-2019-001196.

Abstract

OBJECTIVE

To quantify the implementation of the third Joint British Societies' Consensus Recommendations for the Prevention of Cardiovascular Disease (JBS3) after coronary event.

METHODS

Using a cross-sectional survey design, patients were consecutively identified in 36 specialist and district general hospitals between 6 months and 2 years, after acute coronary syndrome or revascularisation procedure and invited to a research interview. Outcomes included JBS3 lifestyle, risk factor and therapeutic management goals. Data were collected using standardised methods and instruments by trained study nurses. Blood was analysed in a central laboratory and a glucose tolerance test was performed.

RESULTS

3926 eligible patients were invited to participate and 1177 (23.3% women) were interviewed (30% response). 12.5% were from black and minority ethnic groups. 45% were persistent smokers, 36% obese, 52.9% centrally obese, 52% inactive; 30% had a blood pressure >140/90 mm Hg, 54% non-high-density lipoprotein ≥2.5 mmol/L and 44.3% had new dysglycaemia. Prescribing was highest for antiplatelets (94%) and statins (85%). 81% were advised to attend cardiac rehabilitation (86% <60 years vs 79% ≥60 years; 82% men vs 77% women; 93% coronary artery bypass grafting vs 59% unstable angina), 85% attended if advised; 69% attended overall. Attenders were significantly younger (p=0.03) and women were less likely to attend (p=0.03).

CONCLUSIONS

Patients with coronary heart disease (CHD) are not being adequately managed after event with preventive measures. They require a structured preventive cardiology programme addressing lifestyle, risk factor management and adherence to cardioprotective medications to achieve the standards set by the British Association for Cardiovascular Prevention and Rehabilitation and JBS3 guidelines.

摘要

目的

量化冠状动脉事件后英国社会预防心血管疾病联合共识第三次推荐(JBS3)的实施情况。

方法

采用横断面调查设计,在36家专科医院和地区综合医院中,于急性冠状动脉综合征或血运重建术后6个月至2年连续识别患者,并邀请其参加研究访谈。结果包括JBS3生活方式、危险因素及治疗管理目标。数据由经过培训的研究护士使用标准化方法和工具收集。血液在中心实验室进行分析,并进行葡萄糖耐量试验。

结果

3926名符合条件的患者被邀请参与,1177名(23.3%为女性)接受了访谈(应答率30%)。12.5%来自黑人和少数族裔群体。45%为持续吸烟者,36%肥胖,52.9%为中心性肥胖,52%不活动;30%血压>140/90 mmHg,54%非高密度脂蛋白≥2.5 mmol/L,44.3%有新的血糖异常。抗血小板药物(94%)和他汀类药物(85%)的处方率最高。81%被建议参加心脏康复(<60岁者为86%,≥60岁者为79%;男性为82%,女性为77%;冠状动脉搭桥术者为93%,不稳定型心绞痛者为59%),85%在得到建议后参加;总体参加率为69%。参加者明显更年轻(p = 0.03),女性参加的可能性较小(p = 0.03)。

结论

冠心病患者在事件发生后未得到充分的预防措施管理。他们需要一个结构化的预防心脏病学项目,以解决生活方式、危险因素管理以及坚持使用心脏保护药物等问题,从而达到英国心血管预防与康复协会和JBS3指南设定的标准。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbc0/7228656/e69a58e92a9d/openhrt-2019-001196f01.jpg

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