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子痫前期对足月引产的影响:一项队列研究。

Influence of Preeclampsia on Induction of Labor at Term: A Cohort Study.

机构信息

Department of Obstetrics and Gynecology, Erlangen University Hospital, Erlangen, Germany

Department of Medical Statistics and Biomathematics, University Medical Center Mannheim, Heidelberg University, Heidelberg, Germany.

出版信息

In Vivo. 2020 May-Jun;34(3):1195-1200. doi: 10.21873/invivo.11892.

DOI:10.21873/invivo.11892
PMID:32354909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7279832/
Abstract

BACKGROUND/AIM: Even though vaginal delivery is a feasible option in patients with preeclampsia, the cesarean section rate in those patients is high. The aim of this study was to evaluate the influence of preeclampsia on induction of labor at term.

PATIENTS AND METHODS

This historical cohort study analyzed inductions of labor in women at term having preeclampsia versus women who were induced due to other reasons. The primary outcome measure was the cesarean section rate.

RESULTS

The cesarean section rate was higher in the preeclampsia group for both nulliparous and multiparous women after induction of labor but failed to reach statistical significane. The induction-to-delivery interval was longer in nulliparous women and the rate of vaginal birth within 48 h was lower in the nulliparous patiens with preeclampsia. However, the impact of preeclampsia on the cesarean section rate was not significant in the multivariable analysis following adjustment for BMI and parity.

CONCLUSION

Preeclampsia at term did not influence the cesarean section rate in nulliparous and parous women when labor was induced.

摘要

背景/目的:尽管阴道分娩是子痫前期患者的可行选择,但这些患者的剖宫产率仍然很高。本研究旨在评估子痫前期对足月引产的影响。

患者和方法

这项回顾性队列研究分析了子痫前期患者与因其他原因引产的患者之间足月引产的情况。主要观察指标是剖宫产率。

结果

无论是初产妇还是经产妇,子痫前期组在引产时的剖宫产率均高于其他原因引产组,但未达到统计学意义。初产妇的引产至分娩间隔时间较长,且子痫前期初产妇在 48 小时内阴道分娩的比例较低。然而,在调整 BMI 和产次后进行多变量分析,子痫前期对剖宫产率的影响并不显著。

结论

当进行引产时,足月时的子痫前期并未影响初产妇和经产妇的剖宫产率。

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本文引用的文献

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Does induction of labour in nulliparous hypertensive women result in vaginal birth? - A descriptive study utilising birth registry data.未生育的高血压女性引产会导致阴道分娩吗?——一项利用出生登记数据的描述性研究。
Pregnancy Hypertens. 2018 Apr;12:16-22. doi: 10.1016/j.preghy.2018.01.010. Epub 2018 Jan 31.
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Intrauterine Growth Restriction. Guideline of the German Society of Gynecology and Obstetrics (S2k-Level, AWMF Registry No. 015/080, October 2016).宫内生长受限。德国妇产科学会指南(S2k级别,德国医学专业协会注册编号015/080,2016年10月)
Geburtshilfe Frauenheilkd. 2017 Nov;77(11):1157-1173. doi: 10.1055/s-0043-118908. Epub 2017 Nov 27.
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Effect of Premature Rupture of Membranes on Induction of Labor: A Historical Cohort Study.胎膜早破对引产的影响:一项历史性队列研究
Geburtshilfe Frauenheilkd. 2017 Nov;77(11):1174-1181. doi: 10.1055/s-0043-121007. Epub 2017 Nov 27.
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Maternal and Neonatal Outcomes of Induction of Labor Compared with Planned Cesarean Delivery in Women with Preeclampsia at 34 Weeks' Gestation or Longer.34 孕周及以上子痫前期孕妇计划性剖宫产与引产的母婴结局比较
Am J Perinatol. 2018 Jan;35(1):95-102. doi: 10.1055/s-0037-1606185. Epub 2017 Aug 24.
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Diagnosis and Treatment of Hypertensive Pregnancy Disorders. Guideline of DGGG (S1-Level, AWMF Registry No. 015/018, December 2013).妊娠期高血压疾病的诊断与治疗。德国妇产科学会指南(S1级,德国医学专业协会注册编号015/018,2013年12月)
Geburtshilfe Frauenheilkd. 2015 Sep;75(9):900-914. doi: 10.1055/s-0035-1557924.
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Quality Requirements for Ultrasound Examination in Early Pregnancy (DEGUM Level I) between 4+0 and 13+6 Weeks of Gestation.妊娠4+0至13+6周早期妊娠超声检查(德国妇产科和妇女超声学会一级)的质量要求
Ultraschall Med. 2016 Dec;37(6):579-583. doi: 10.1055/s-0042-115581. Epub 2016 Sep 14.
7
Caesarean section rates and adverse neonatal outcomes after induction of labour versus expectant management in women with an unripe cervix: a secondary analysis of the HYPITAT and DIGITAT trials.剖宫产率和未成熟宫颈产妇引产与期待治疗后不良新生儿结局:HYPITAT 和 DIGITAT 试验的二次分析。
BJOG. 2016 Aug;123(9):1501-8. doi: 10.1111/1471-0528.14028. Epub 2016 May 13.
8
Maternal outcomes according to mode of delivery in women with severe preeclampsia: a cohort study.重度子痫前期女性分娩方式的母儿结局:一项队列研究
J Matern Fetal Neonatal Med. 2015 Apr;28(6):654-60. doi: 10.3109/14767058.2014.928689. Epub 2014 Jun 30.
9
Pre-eclampsia, eclampsia and adverse maternal and perinatal outcomes: a secondary analysis of the World Health Organization Multicountry Survey on Maternal and Newborn Health.子痫前期、子痫和不良母婴围产结局:世界卫生组织母婴健康调查的二次分析。
BJOG. 2014 Mar;121 Suppl 1:14-24. doi: 10.1111/1471-0528.12629.
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