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影响单光子发射计算机断层扫描（SPECT）图像质量的不同因素研究：一项模拟研究

Investigation of Different Factors Affecting the Quality of SPECT Images: A Simulation Study.

作者信息

Noori-Asl Mahsa

机构信息

Department of Physics, Faculty of Science, University of Mohaghegh Ardabili, Ardabil, Iran.

出版信息

J Med Phys. 2020 Jan-Mar;45(1):44-51. doi: 10.4103/jmp.JMP_88_19. Epub 2020 Mar 13.

DOI:10.4103/jmp.JMP_88_19
PMID:32355434
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7185706/
Abstract

BACKGROUND

Monte Carlo (MC) simulation codes are used extensively for modeling the nuclear medicine imaging systems, such as single photon emission computed tomography (SPECT) and positron emission tomography (PET). By using these codes, it is possible to set different imaging parameters and do various studies in the field of nuclear medicine imaging.

AIMS AND OBJECTIVES

The aim of this study is to investigate the effective factors in improvement of the SPECT image quality by using MC simulation.

MATERIALS AND METHODS

In this study, we used the SIMIND MC simulation code and Jaszczak phantom containing six spheres with different diameters placed into a water-filled cylindrical phantom for consideration of the effects of different factors on quality of the images obtained from Tc-99m SPECT imaging system. The assessment criteria used to investigate these factors included image contrast, signal-to-noise ratio (SNR) and relative noise of the background (RNB).

RESULTS

The results of this study show that the right choice of the arc of rotation, the image matrix size, the number of angular views, type of the collimators, and also filters used in the image reconstruction affect the quality of SPECT images. Also, we show that use of scatter correction methods can improve the image quality.

CONCLUSION

The MC simulation is a suitable tool for investigation of different factors affecting the quality of SPECT images, essentially in the studies based on the energy spectrum, such as the evaluation of the scatter correction methods.

摘要

背景

蒙特卡罗（MC）模拟代码被广泛用于对核医学成像系统进行建模，如单光子发射计算机断层扫描（SPECT）和正电子发射断层扫描（PET）。通过使用这些代码，可以设置不同的成像参数并在核医学成像领域开展各种研究。

目的

本研究旨在通过MC模拟探究改善SPECT图像质量的影响因素。

材料与方法

在本研究中，我们使用SIMIND MC模拟代码以及贾兹扎克体模，该体模包含六个不同直径的球体，放置在一个充满水的圆柱形体模中，以考虑不同因素对从Tc-99m SPECT成像系统获得的图像质量的影响。用于研究这些因素的评估标准包括图像对比度、信噪比（SNR）和背景相对噪声（RNB）。

结果

本研究结果表明，旋转弧、图像矩阵大小、角度视图数量、准直器类型以及图像重建中使用的滤波器的正确选择会影响SPECT图像的质量。此外，我们表明使用散射校正方法可以提高图像质量。

结论

MC模拟是研究影响SPECT图像质量的不同因素的合适工具，尤其是在基于能谱的研究中，如散射校正方法的评估。

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本文引用的文献

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J Cancer Res Ther. 2017 Oct-Dec;13(6):936-942. doi: 10.4103/jcrt.JCRT_1085_16.
2
The development and evaluation of a medical imaging training immersive environment.医学影像训练沉浸式环境的开发与评估
J Med Radiat Sci. 2014 Sep;61(3):159-65. doi: 10.1002/jmrs.60. Epub 2014 Jun 30.
3
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Phys Med. 2014 Dec;30(8):947-53. doi: 10.1016/j.ejmp.2014.05.008. Epub 2014 Jun 28.
4
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5
The accuracy of absorbed dose estimates in tumours determined by quantitative SPECT: a Monte Carlo study.定量 SPECT 测定肿瘤吸收剂量的准确性：一项蒙特卡罗研究。
Acta Oncol. 2011 Aug;50(6):981-9. doi: 10.3109/0284186X.2011.584559.
6
Filtering in SPECT Image Reconstruction.单光子发射计算机断层显像（SPECT）图像重建中的滤波
Int J Biomed Imaging. 2011;2011:693795. doi: 10.1155/2011/693795. Epub 2011 Jun 23.
7
3-D Monte Carlo-Based Scatter Compensation in Quantitative I-131 SPECT Reconstruction.基于三维蒙特卡罗的定量I-131单光子发射计算机断层扫描重建中的散射补偿
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8
Optimization of energy-window settings for scatter correction in quantitative (111)In imaging: comparison of measurements and Monte Carlo simulations.定量铟-111成像中用于散射校正的能量窗设置优化：测量与蒙特卡罗模拟的比较
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9
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10
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J Nucl Med Technol. 2000 Dec;28(4):233-44.