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记忆功能障碍的自我评定:抑郁症和失忆症中的不同发现。

Self-ratings of memory dysfunction: different findings in depression and amnesia.

作者信息

Squire L R, Zouzounis J A

机构信息

Veterans Administration Medical Center, San Diego, CA 92161.

出版信息

J Clin Exp Neuropsychol. 1988 Dec;10(6):727-38. doi: 10.1080/01688638808402810.

Abstract

An 18-item self-rating test of memory functions was administered to two patient groups: seven patients with amnesia resulting from Korsakoff's syndrome and six other amnesic patients. These results were compared to results obtained previously for depressed psychiatric inpatients (n = 19) and depressed inpatients prescribed electroconvulsive therapy (ECT) (n = 35). The latter group was tested both before and 1 week after completion of the course of ECT. One pattern of memory self-ratings was reported by the two groups of depressed patients. These two groups reported an approximately equivalent level of impairment across all test items. A different pattern of memory self-ratings was reported by the two groups of amnesic patients and by the group tested after ECT. These patients reported considerably more impairment on some items than others, such that performance was not equivalent across test items. Finally, the patients with Korsakoff's syndrome underestimated their memory problems, reporting a less severe impairment than the other amnesic patients. The results show that the memory problems experienced in depression and in amnesia are distinguishable with self-assessment techniques. In addition, the similarity between memory self-ratings reported by patients after ECT and by amnesic patients supports the idea that memory complaints after ECT reflect primarily the experience of amnesia. Self-rating forms like the one described here may have useful application to many diagnostic groups where questions arise about the nature of reported memory problems.

摘要

对两组患者进行了一项包含18个项目的记忆功能自评测试:7名患有科尔萨科夫综合征所致失忆症的患者和6名其他失忆症患者。将这些结果与之前对抑郁精神科住院患者(n = 19)和接受电休克治疗(ECT)的抑郁住院患者(n = 35)所获得的结果进行了比较。后一组患者在ECT疗程结束前和结束后1周均接受了测试。两组抑郁患者报告了一种记忆自评模式。这两组患者在所有测试项目中报告的损伤水平大致相当。两组失忆症患者以及ECT后接受测试的组报告了不同的记忆自评模式。这些患者在某些项目上报告的损伤比其他项目严重得多,以至于各测试项目的表现并不等同。最后,患有科尔萨科夫综合征的患者低估了他们的记忆问题,报告的损伤程度比其他失忆症患者轻。结果表明,通过自我评估技术可以区分抑郁症和失忆症中所经历的记忆问题。此外,ECT后患者与失忆症患者报告的记忆自评之间的相似性支持了这样一种观点,即ECT后的记忆主诉主要反映了失忆症的体验。像这里所描述的自评表格可能对许多出现报告记忆问题性质疑问的诊断组有有用的应用价值。

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