Department of Endocrinology and Metabolism, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Tojinkai Hospital, Kyoto, Japan.
J Diabetes Investig. 2020 Nov;11(6):1570-1574. doi: 10.1111/jdi.13286. Epub 2020 Jun 9.
We aimed to investigate if estimated hemoglobin A1c (eHbA1c) levels determined using a flash continuous glucose monitoring system could be an indicator of glycemic control status in hemodialysis patients with diabetes. Hemodialysis patients with type 2 diabetes were recruited. eHbA1c levels were measured using the FreeStyle Libre Flash Glucose Monitoring System . A total of 18 hemodialysis patients with diabetes were included in the study. The eHbA1c - calculated based on glycated albumin level, and body mass index and serum hemoglobin concentration were also included in the formula - was higher than the eHbA1c in most patients. Furthermore, the eHbA1c - eHbA1c values were >2% in all patients with body mass index <18.5 kg/m ; the maximal value was 4.1%. This study shows that eHbA1c can be used as a reliable indicator for evaluating glycemic control and avoiding hypoglycemia in hemodialysis patients with diabetes, particularly those with decreased body mass index.
我们旨在研究使用闪光连续血糖监测系统测定的估算血红蛋白 A1c（eHbA1c）水平是否可以作为糖尿病血液透析患者血糖控制状况的指标。招募了患有 2 型糖尿病的血液透析患者。使用 FreeStyle Libre Flash 血糖监测系统测量 eHbA1c 水平。共有 18 名患有糖尿病的血液透析患者纳入研究。基于糖化白蛋白水平、体重指数和血清血红蛋白浓度计算的 eHbA1c 也包含在公式中，结果发现 eHbA1c 高于大多数患者的 eHbA1c。此外，所有体重指数<18.5kg/m2的患者的 eHbA1c - eHbA1c 值均>2%；最大值为 4.1%。这项研究表明，eHbA1c 可用于评估糖尿病血液透析患者的血糖控制和避免低血糖，尤其是那些体重指数下降的患者。
