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喷雾干燥法微囊化抗坏血酸:载药量变化对抗坏血酸微囊化粉末理化性质的影响。

Spray-drying microencapsulation of ascorbic acid: impact of varying loading content on physicochemical properties of microencapsulated powders.

机构信息

Technology of Agricultural Products Department, Jambi University, Jambi, Indonesia.

Applied Chemistry, School of Applied Sciences, RMIT University, Melbourne, Victoria, Australia.

出版信息

J Sci Food Agric. 2020 Aug 30;100(11):4165-4171. doi: 10.1002/jsfa.10455. Epub 2020 Jun 3.

DOI:10.1002/jsfa.10455
PMID:32356902
Abstract

BACKGROUND

There is increased interest in the food, pharmaceutical and cosmetic industries in using ascorbic acid as an important component in the human diet for health support and disease prevention. However, its use as an ingredient is limited by its high instability and sensitivity to environmental conditions. Microencapsulation technology has been proposed to increase the stability of ascorbic acid. The aim this work was to evaluate the effect of ascorbic acid loading rate on the physicochemical properties of encapsulated ascorbic acid. Loading contents of ascorbic acid of 6%, 9%, 18%, 36%, 54% and 72% were trialled using spray drying in conjunction with starch-based encapsulating agents.

RESULTS

The results showed that the loading content has a significant effect on ascorbic acid retention, yield, moisture content, water activity, colour change, particle size and distribution of microcapsules. Morphology of microcapsules also was assessed using environmental scanning electron microscopy, showing that the microcapsules had good structure and integrity for a loading content of 18% and even as high as 54%. At levels beyond this, capsules showed a lack of coherence and integrity of the outer shell.

CONCLUSIONS

The results indicated that ascorbic acid microparticles at various loading rates have a substantial impact on physical and chemical properties of microcapsules. Loading content can be selected to ensure colour uniformity and minimal effects on colour during food fortification processes. © 2020 Society of Chemical Industry.

摘要

背景

食品、制药和化妆品行业越来越关注将抗坏血酸作为人类饮食的重要组成部分,以支持健康和预防疾病。然而,由于其高不稳定性和对环境条件的敏感性,其作为一种成分的使用受到限制。微胶囊化技术已被提议用于提高抗坏血酸的稳定性。本工作旨在评估抗坏血酸负载率对抗坏血酸包封的物理化学性质的影响。使用喷雾干燥法结合基于淀粉的包封剂,尝试了 6%、9%、18%、36%、54%和 72%的抗坏血酸负载含量。

结果

结果表明,负载含量对抗坏血酸保留率、产率、水分含量、水分活度、颜色变化、微胶囊的粒径和分布有显著影响。使用环境扫描电子显微镜评估了微胶囊的形态,结果表明,对于 18%的负载含量,甚至高达 54%的负载含量,微胶囊具有良好的结构和完整性。在超过这个水平的情况下,胶囊表现出外壳的不连贯性和完整性缺失。

结论

结果表明,不同负载率的抗坏血酸微颗粒对微胶囊的物理和化学性质有很大的影响。可以选择负载含量,以确保在食品强化过程中颜色均匀,颜色影响最小。© 2020 英国化学学会。

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