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一种采用静电纺丝制备的可颜色检测的维生素C控释系统。

A Color-Detectable Vitamin C Controlled-Release System Fabricated Using Electrospinning.

作者信息

Shin Min Jae

机构信息

Department of Chemical and Biological Engineering, Andong National University, Andong 36729, Gyeongbuk, Republic of Korea.

出版信息

Polymers (Basel). 2024 May 9;16(10):1347. doi: 10.3390/polym16101347.

DOI:10.3390/polym16101347
PMID:38794540
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11125048/
Abstract

This study develops a vitamin C controlled-release system, trackable via color changes as a function of vitamin C release. The system is composed of coaxial microfibers prepared via coaxial electrospinning, with a core of poly(ethylene oxide) (PEO) incorporating vitamin C, and a shell composed of polycaprolactone (PCL) containing polydiacetylene (PDA) as the color-changing material. The shell thickness is controlled by adjusting the amount of PCL ejected during electrospinning, allowing regulation of the release rate of vitamin C. When vitamin C added to PEO penetrates the PCL layer, the color of PDA changes from blue to red, indicating a color change. The results of this study can be applied to devices that require immediate detection of vitamin C release levels.

摘要

本研究开发了一种维生素C控释系统，可通过随维生素C释放而变化的颜色改变进行追踪。该系统由通过同轴静电纺丝制备的同轴微纤维组成，其核心是掺入维生素C的聚环氧乙烷（PEO），外壳由含有聚二乙炔（PDA）作为变色材料的聚己内酯（PCL）组成。通过调节静电纺丝过程中喷出的PCL量来控制外壳厚度，从而调节维生素C的释放速率。当添加到PEO中的维生素C穿透PCL层时，PDA的颜色从蓝色变为红色，表明发生了颜色变化。本研究结果可应用于需要即时检测维生素C释放水平的装置。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fd/11125048/f0aab03c14b2/polymers-16-01347-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fd/11125048/aedc8cac13c4/polymers-16-01347-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fd/11125048/691298969179/polymers-16-01347-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fd/11125048/7c746b3da5a4/polymers-16-01347-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fd/11125048/ad61d35b83b1/polymers-16-01347-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fd/11125048/b975a1228675/polymers-16-01347-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fd/11125048/a4dfeef9f5a9/polymers-16-01347-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fd/11125048/f0aab03c14b2/polymers-16-01347-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fd/11125048/aedc8cac13c4/polymers-16-01347-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fd/11125048/691298969179/polymers-16-01347-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fd/11125048/7c746b3da5a4/polymers-16-01347-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fd/11125048/ad61d35b83b1/polymers-16-01347-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fd/11125048/b975a1228675/polymers-16-01347-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fd/11125048/a4dfeef9f5a9/polymers-16-01347-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fd/11125048/f0aab03c14b2/polymers-16-01347-g007.jpg

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2
Vitamin C fortification: need and recent trends in encapsulation technologies.维生素C强化：需求及包囊技术的最新趋势
Front Nutr. 2023 Sep 7;10:1229243. doi: 10.3389/fnut.2023.1229243. eCollection 2023.
3
Encapsulation of Vitamins Using Nanoliposome: Recent Advances and Perspectives.利用纳米脂质体包封维生素：最新进展与展望
Adv Pharm Bull. 2023 Jan;13(1):48-68. doi: 10.34172/apb.2023.005. Epub 2021 Oct 10.
4
Encapsulation of Vitamin C by Glycerol-Derived Dendrimers, Their Interaction with Biomimetic Models of and Their Cytotoxicity.甘油衍生树状大分子包封维生素 C 及其与 类生物模型的相互作用和细胞毒性。
Molecules. 2022 Nov 18;27(22):8022. doi: 10.3390/molecules27228022.
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Ascorbic Acid (Vitamin C) as a Cosmeceutical to Increase Dermal Collagen for Skin Antiaging Purposes: Emerging Combination Therapies.抗坏血酸（维生素C）作为一种用于增加真皮胶原蛋白以实现皮肤抗老化目的的药妆品：新兴联合疗法。
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6
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RSC Adv. 2019 Aug 15;9(44):25712-25729. doi: 10.1039/c9ra05012d. eCollection 2019 Aug 13.
7
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