Delaporte Adeline, Duchemin Benoît, Grisel Michel, Gore Ecaterina
Université Le Havre Normandie, Normandie Univ, URCOM UR 3221, F-76600 Le Havre, France.
Université Le Havre Normandie, Normandie Univ, CNRS, LOMC, F-76600 Le Havre, France.
Molecules. 2024 Jul 30;29(15):3587. doi: 10.3390/molecules29153587.
Encapsulation revolutionizes industries through enhanced stability, controlled release, and targeted performance of active ingredients. The novel aspect of this study explores the impact of the wall material-to-active (WM:A) ratio on the stability of ascorbic acid (AA) encapsulated in a maltodextrin (MD) and gum arabic (GA) blend (2:1 ). Microparticles were spray-dried and analyzed using SEM, TGA, DSC, thermal stability, and antioxidant activity assessments. Stability tests under different conditions revealed that a higher WM:A ratio (7:1) improved the active stability and antioxidant activity during storage, highlighting its importance in the encapsulation process. SEM analysis confirmed particles with no cracks, and the particles demonstrated excellent thermal stability up to 200 °C with minimal degradation. These findings underscore the critical role of the WM:A ratio in determining the stability of encapsulated AA within a carbohydrate matrix, offering valuable insights for advancing encapsulation technologies.
包封通过提高活性成分的稳定性、控制释放和靶向性能,给各行业带来了变革。本研究的新颖之处在于探索壁材与活性成分(WM:A)比例对包封在麦芽糊精(MD)和阿拉伯胶(GA)混合物(2:1)中的抗坏血酸(AA)稳定性的影响。对微粒进行喷雾干燥,并使用扫描电子显微镜(SEM)、热重分析(TGA)、差示扫描量热法(DSC)、热稳定性和抗氧化活性评估进行分析。不同条件下的稳定性测试表明,较高的WM:A比例(7:1)提高了储存期间的活性稳定性和抗氧化活性,突出了其在包封过程中的重要性。扫描电子显微镜分析证实微粒无裂缝,并且这些微粒在高达200°C时表现出优异的热稳定性,降解极少。这些发现强调了WM:A比例在确定碳水化合物基质中包封的AA稳定性方面的关键作用,为推进包封技术提供了有价值的见解。