Department of Ophthalmology, Ekol Eye Hospital, 8019/13 str. No:2 Çigli, İzmir, Turkey.
İzmir Tepecik Training and Research Hospital, Ophthalmology Clinic, University of Health Sciences, Izmir, Turkey.
Int Ophthalmol. 2020 Sep;40(9):2169-2178. doi: 10.1007/s10792-020-01397-2. Epub 2020 May 1.
The aim of this study was to compare wavefront aberrations before and after Nd:YAG capsulotomy in multifocal intraocular lens (MfIOL) and monofocal (MoIOL) pseudophakic eyes with posterior capsule opacification (PCO).
Wavefront aberrations were measured using a ARK-10000 topographer before and after Nd:YAG capsulotomy in eyes that underwent MfIOL or MoIOL implantation and developed PCO. Total and higher-order aberrations (HOAs) values were evaluated as root mean square (RMS).
The study included 64 eyes with MfIOLs (64 patients) and 72 with MoIOLs (72 patients) that developed PCO. Total RMS values before and 1 month after Nd:YAG capsulotomy were 0.863 ± 0.27 and 0.504 ± 0.24 in the MFIOL group and 0.862 ± 0.31 and 0.466 ± 0.26 in the MoIOL group, respectively. Total RMS values did not differ significantly between the groups before (p = 0.914) or 1 month after Nd:YAG laser capsulotomy (p = 0.357), but decreased significantly after Nd:YAG capsulotomy compared to baseline in both the MfIOL (p = 0.027) and MoIOL (p = 0.012) groups. HOA values before and 1 month after Nd:YAG capsulotomy were 0.546 ± 0.23 and 0.364 ± 0.19 in the MfIOL group and 0.500 ± 0.21 and 0.346 ± 0.18 in the MoIOL group, respectively. HOA values did not differ significantly before (p = 0.828) or after Nd:YAG capsulotomy (p = 0.111), while both groups showed significant reduction in HOAs after Nd:YAG capsulotomy (MfIOL: p = 0.021, MoIOL: p = 0.027).
Nd:YAG capsulotomy reduces total and HOAs to the same extent in eyes with both MfIOLs and MoIOLs, with no significant impact of the IOL design.
本研究旨在比较多焦点人工晶状体（MfIOL）和单焦点（MoIOL）后发性白内障患者行 Nd:YAG 囊膜切开术后眼的波前像差。
使用 ARK-10000 地形图仪测量 MfIOL 或 MoIOL 植入术后发生后发性白内障的眼在 Nd:YAG 囊膜切开术前和术后的波前像差。总像差和高阶像差（HOA）值以均方根（RMS）表示。
本研究共纳入 64 例 MfIOL 眼（64 例患者）和 72 例 MoIOL 眼（72 例患者），这些眼均患有后发性白内障。MfIOL 组 Nd:YAG 囊膜切开术前和术后 1 个月的总 RMS 值分别为 0.863±0.27 和 0.504±0.24，MoIOL 组分别为 0.862±0.31 和 0.466±0.26。Nd:YAG 激光囊膜切开术前（p=0.914）和术后 1 个月（p=0.357）两组间总 RMS 值无显著差异，但 MfIOL 组（p=0.027）和 MoIOL 组（p=0.012）Nd:YAG 囊膜切开术后均较基线值显著降低。MfIOL 组 Nd:YAG 囊膜切开术前和术后 1 个月的 HOA 值分别为 0.546±0.23 和 0.364±0.19，MoIOL 组分别为 0.500±0.21 和 0.346±0.18。Nd:YAG 囊膜切开术前（p=0.828）和术后（p=0.111）两组间 HOA 值无显著差异，但两组术后 HOA 均显著降低（MfIOL：p=0.021，MoIOL：p=0.027）。
Nd:YAG 囊膜切开术可同等程度地降低 MfIOL 和 MoIOL 眼的总像差和高阶像差，对人工晶状体设计无显著影响。
