Department of Ophthalmology (Qvision), VITHAS Hospital, 04120, Almería, Spain.
Department of Ophthalmology, Carlos Haya University Regional Hospital, 29010, Málaga, Spain.
Graefes Arch Clin Exp Ophthalmol. 2021 Oct;259(10):2995-3002. doi: 10.1007/s00417-021-05262-5. Epub 2021 Jun 10.
To assess the degree of posterior capsular opacification (PCO) and its influence on contrast sensitivity defocus curve (CSDC) after implantation of two trifocal intraocular lenses (IOLs), Alsafit (AT) and Liberty (L), during a 12-month follow-up. A secondary aim was to evaluate the Nd:YAG capsulotomy rate in a long time.
Data from 63 subjects, 34 implanted with AT and 29 with L, were retrospectively analyzed for this pilot study. In those eyes without capsulotomy during the first year (n = 58), CSDC at 3 and 12 months after surgery and PCO grading were measured, with additional answering of a visual function questionnaire (VF-14) and a question of general satisfaction. The period after surgery up to capsulotomy or last on-demand visit without Nd:YAG was recorded for survival analysis beyond the 12-month follow-up.
Total area under CSDC (TAUC) between 3 and 12 months decreased from 2.96 to 1.71 for AT (p < 0.05) and from 2.73 to 2.21 (p > 0.05) for L. Of eyes, 51.6, 19.3, and 29% with AT were graded as level 0, 1, and 2 of PCO, while 85.1, 11.1, and 3.7% of eyes with L were graded as level 0, 1, and 2 (p < 0.05). PCO grading was correlated with a decrease of TAUC (ρ = - 0.27, p = 0.04). Median time to require capsulotomy was 22 months with AT and 30 months with L (p < 0.05).
PCO decreases CSDC in patients with trifocal lenses. Despite using the same hydrophilic material, PCO grading and Nd:YAG capsulotomy rate was higher for AT than for L.
评估植入两种三焦点人工晶状体（IOL）——Alsafit（AT）和 Liberty（L）后 12 个月内后囊混浊（PCO）的程度及其对对比敏感度离焦曲线（CSDC）的影响。次要目的是评估长时间内 Nd：YAG 后囊切开术的发生率。
对 63 名患者（植入 AT 者 34 名，植入 L 者 29 名）的数据进行回顾性分析，以进行这项初步研究。在第一年未行后囊切开术的 58 只眼中（n=58），测量术后 3 个月和 12 个月的 CSDC 和 PCO 分级，并额外回答视觉功能问卷（VF-14）和一般满意度问题。记录术后至后囊切开术或最后一次按需就诊（无 Nd：YAG）的时间，以进行 12 个月随访后的生存分析。
AT 的 CSDC 总曲线下面积（TAUC）从术后 3 个月的 2.96 降至 12 个月的 1.71（p<0.05），而 L 的 TAUC 从术后 3 个月的 2.73 降至 12 个月的 2.21（p>0.05）。AT 的 51.6%、19.3%和 29%的眼被分级为 PCO 的 0、1 和 2 级，而 L 的 85.1%、11.1%和 3.7%的眼被分级为 0、1 和 2 级（p<0.05）。PCO 分级与 TAUC 下降相关（ρ=−0.27，p=0.04）。AT 需行后囊切开术的中位时间为 22 个月，L 为 30 个月（p<0.05）。
三焦点晶状体患者的 PCO 会降低 CSDC。尽管使用了相同的亲水性材料，但 AT 的 PCO 分级和 Nd：YAG 后囊切开术发生率高于 L。
