Faculty of Nutrition and Food Sciences, University of Porto, Porto, Portugal; Universidade Federal do Maranhão, Brazil.
Faculty of Nutrition and Food Sciences, University of Porto, Porto, Portugal; CINTESIS Center for Health Technology & Services Research, Rua Dr Placido da Costa, 4200-450, Porto, Portugal.
Clin Nutr ESPEN. 2020 Jun;37:240-246. doi: 10.1016/j.clnesp.2020.02.006. Epub 2020 Mar 20.
Correct measurement of resting energy expenditure (REE) is essential to offer a proper nutritional management during hospital stay. Dietitians are not able to perform an effective dietary treatment if predicted REE values are obtained from invalid equations.
The aim of this study was to develop a more valid method to estimate REE in non-critically ill Portuguese patients.
In this cross-sectional study, REE was measured by indirect calorimetry (IC) in 180 non-critically patients during hospital stay (50 participants were allocated to the validation group by simple randomization and the remaining 130 were allocated to the derivation group). The best accurate equations were derived by multiple linear regression analysis (stepwise) based on anthropometric variables. The equations were tested on the validation group and compared with published predictive equations.
Data was collected from 130 patients, 68 women (52.3%) and 62 men (47.7%), mean age was 58.9 ± 16.8 years and REE-IC was 1918 ± 721 kcal/day. The new best-fit equation REE (kcal/day) = 14.4 (Height) + 52.7 (MUAC) + 453.4 (1 if male, 0 if female) - 371.2 (if Obese) - 2138.3 showed strength of evidence decisive (BF₁₀ = 8008), when compared by Bayesian model, and r = 0.315. Only estimated REE values obtained using new equations did not present significant difference when compared with measured REE values (kcal/kg).
In this study, new equations derived from a non-critically ill population showed higher validity in estimating REE than currently used equations. A better estimation of REE may lead to a better nutritional intervention and a decreased risk of undernutrition in hospitalized patients.
准确测量静息能量消耗（REE）对于在住院期间提供适当的营养管理至关重要。如果通过无效的方程获得预测的 REE 值，营养师将无法进行有效的饮食治疗。
本研究旨在开发一种更有效的方法来估计非危重病葡萄牙患者的 REE。
在这项横断面研究中，通过间接热量法（IC）在住院期间测量了 180 名非危重病患者的 REE（通过简单随机分组将 50 名参与者分配到验证组，其余 130 名参与者分配到推导组）。根据人体测量变量，通过多元线性回归分析（逐步法）得出最准确的方程。在验证组中测试这些方程，并与已发表的预测方程进行比较。
从 130 名患者中收集了数据，其中 68 名女性（52.3%）和 62 名男性（47.7%），平均年龄为 58.9±16.8 岁，REE-IC 为 1918±721kcal/天。新的最佳拟合方程 REE（kcal/天）=14.4（身高）+52.7（MUAC）+453.4（男性为 1，女性为 0）-371.2（肥胖）-2138.3，当与贝叶斯模型进行比较时，证据强度为决定性（BF₁₀=8008），并且 r=0.315。与测量的 REE 值（kcal/kg）相比，仅使用新方程估计的 REE 值没有显著差异。
在这项研究中，从非危重病患者群体中得出的新方程在估计 REE 方面比目前使用的方程具有更高的有效性。REE 的更好估计可能导致更好的营养干预，并降低住院患者发生营养不良的风险。
