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[孕期主动吸烟的后果 - CNGOF-SFT专家报告及孕期吸烟管理指南]

[Consequences of Active Cigarette Smoking in Pregnancy - CNGOF-SFT Expert Report and Guidelines on the management of smoking during pregnancy].

作者信息

Diguisto C, Dochez V

机构信息

Service de gynécologie obstétrique, maternité Olympe de Gouges, université François-Rabelais, centre hospitalier universitaire de Tours, 37100 Tours, France.

Service de gynécologie obstétrique, centre hospitalier universitaire de Nantes, 44093 Nantes cedex 1, France.

出版信息

Gynecol Obstet Fertil Senol. 2020 Jul-Aug;48(7-8):559-566. doi: 10.1016/j.gofs.2020.03.025. Epub 2020 Apr 30.

DOI:10.1016/j.gofs.2020.03.025
PMID:32360705
Abstract

OBJECTIVE

To synthesize knowledge on the consequences of active smoking in pregnancy.

METHODS

The MedLine database, the Cochrane Library and French and foreign guidelines from 1999 to 2019 have been consulted.

RESULTS

Active maternal smoking is associated with an increased risk of first trimester complications such as early miscarriage and ectopic pregnancy with a dose-effect relationship between smoking and those risks. Active cigarette smoking during pregnancy is associated with an increased risk of certain type of birth defects, placenta abruptio, placenta previa, stillbirth and cesarean delivery. Active maternal smoking is associated with a reduced risk of pre-eclampsia. Children born to mothers who smoke are more at risk of premature birth and low birth weight with a dose-effect relationship for those two risks.

CONCLUSION

Apart from preeclampsia which is reduced in case of active maternal smoking, perinatal morbidity is increased among women who smoke during their pregnancy.

摘要

目的

综合关于孕期主动吸烟后果的知识。

方法

查阅了1999年至2019年的医学在线数据库、考克兰图书馆以及法国和国外的指南。

结果

母亲主动吸烟与孕早期并发症风险增加相关,如早期流产和异位妊娠,吸烟与这些风险之间存在剂量效应关系。孕期主动吸烟与某些类型出生缺陷、胎盘早剥、前置胎盘、死产和剖宫产风险增加相关。母亲主动吸烟与子痫前期风险降低相关。吸烟母亲所生子女早产和低出生体重风险更高,这两种风险存在剂量效应关系。

结论

除了母亲主动吸烟可降低子痫前期风险外,孕期吸烟的女性围产期发病率会增加。

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