Grönniger J, Georgi M
Leber Magen Darm. 1977 Apr;7(2):75-83.
66 patients suffering from tumors of the small intestine were operated upon between 1963 and 1976 in the Surgical Department of the University of Mainz Medical School. In 16 cases benign tumors were found (6 neurinoma, 4 leiomyoma, 4 lipoma, 2 polyps), in 50 cases the tumors were malignant (24 carcinoma, 20 sarcoma, 2 malignant schwannoma, 4 carcinoids). Only in 12 patients surgery was radical and no metastases found. In more than one third of the patients surgery had to be done as an emergency operation because of life threatening complications. The correct diagnosis was established preoperatively only in 57.5% of all cases. Only 5 out of 15 patients still living have survived more than 5 years. Correct interpretation of early clinical symptoms, repeated X-ray studies and additional chemotherapy may improve the prognosis of malignant tumors of the small intestine.
1963年至1976年间,美因茨大学医学院外科对66例小肠肿瘤患者进行了手术。其中发现良性肿瘤16例(神经鞘瘤6例、平滑肌瘤4例、脂肪瘤4例、息肉2例),恶性肿瘤50例(癌24例、肉瘤20例、恶性神经鞘瘤2例、类癌4例)。只有12例患者接受了根治性手术且未发现转移。超过三分之一的患者因危及生命的并发症而不得不进行急诊手术。术前仅在57.5%的病例中做出了正确诊断。15名仍在世的患者中只有5人存活超过了5年。正确解读早期临床症状、反复进行X线检查以及辅助化疗可能会改善小肠恶性肿瘤的预后。