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新冠康复患者的随访研究——有必要吗?

Follow-up studies in COVID-19 recovered patients - is it mandatory?

机构信息

Human Molecular Cytogenetics and Stem Cell Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore 641 046, Tamil Nadu, India.

Department of Zoology, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore 641 043, Tamil Nadu, India.

出版信息

Sci Total Environ. 2020 Aug 10;729:139021. doi: 10.1016/j.scitotenv.2020.139021. Epub 2020 Apr 27.

DOI:10.1016/j.scitotenv.2020.139021
PMID:32360909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7184970/
Abstract

The novel Coronavirus disease 2019 (COVID-19) is an illness caused due to Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The World Health Organization (WHO) has declared this outbreak a global health emergency and as on April 24, 2020, it has spread to 213 countries, with 25,91,015 confirmed cases and 742,855 cases have been recovered from COVID-19. In this dreadful situation our team has already published an article in the Science of the Total Environment, which elaborates the various aspects of the SARS-CoV-2 infection. In this situation, it is imperative to understand the possible outcome of COVID-19 recovered patients and determine if they have any other detrimental illnesses by longitudinal analysis to safeguard their life in future. It is necessary to follow-up these recovered patients and performs comprehensive assessments for detection and appropriate management towards their psychological, physical, and social realm. This urges us to suggest that it is highly important to provide counselling, moral support as well as a few recommended guidelines to the recovered patients and society to restore to normalcy. Epidemiological, clinical and immunological studies from COVID-19 recovered patients are particularly important to understand the disease and to prepare better for potential outbreaks in the future. Longitudinal studies on a larger cohort would help us to understand the in-depth prognosis as well as the pathogenesis of COVID-19. Also, follow-up studies will help us provide more information for the development of vaccines and drugs for these kinds of pandemics in the future. Hence, we recommend more studies are required to unravel the possible mechanism of COVID-19 infection and the after-effects of it to understand the characteristics of the virus and to develop the necessary precautionary measures to prevent it.

摘要

新型冠状病毒病 2019(COVID-19)是由严重急性呼吸系统综合征冠状病毒 2 型(SARS-CoV-2)引起的疾病。世界卫生组织(WHO)已宣布此次疫情为全球卫生紧急事件,截至 2020 年 4 月 24 日,该病毒已传播至 213 个国家,确诊病例达 2591015 例,COVID-19 康复病例达 742855 例。在这种可怕的情况下,我们的团队已经在《整体环境科学》杂志上发表了一篇文章,详细阐述了 SARS-CoV-2 感染的各个方面。在这种情况下,有必要通过纵向分析了解 COVID-19 康复患者的可能结果,并确定他们是否有任何其他不利的疾病,以保障他们未来的生命。有必要对这些康复患者进行随访,并对他们的心理、身体和社会领域进行全面评估,以发现和进行适当的管理。这促使我们建议,向康复患者和社会提供咨询、道义支持以及一些建议性指导方针是非常重要的,以帮助他们恢复正常生活。从 COVID-19 康复患者中进行的流行病学、临床和免疫学研究对于了解该疾病以及为未来可能的疫情做好更好的准备特别重要。对更大队列进行纵向研究将有助于我们深入了解 COVID-19 的预后和发病机制。此外,随访研究将有助于我们提供更多信息,以开发针对此类大流行的疫苗和药物。因此,我们建议进行更多研究,以揭示 COVID-19 感染的可能机制及其后果,以了解该病毒的特征,并制定必要的预防措施以防止感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f00/7184970/554dd7c5c272/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f00/7184970/4fa691e9c533/ga1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f00/7184970/554dd7c5c272/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f00/7184970/4fa691e9c533/ga1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f00/7184970/554dd7c5c272/gr1_lrg.jpg

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