Hefei National Laboratory for Physical Sciences at Microscale, School of Life Sciences, University of Science and Technology of China, Anhui, 230027, Hefei, China.
Biomol NMR Assign. 2020 Oct;14(2):201-203. doi: 10.1007/s12104-020-09945-8. Epub 2020 May 2.
LW domain is the N-terminal domain I of transcription elongation factor TFIIS, which is a component of RNA polymerase II (Pol II) preinitiation complexes (PICs). Here, we report the resonance assignments of TFIIS LW domain from Homo sapiens for further understanding of the relationship between its structure and function.
LW 结构域是转录延伸因子 TFIIS 的 N 端结构域 I,是 RNA 聚合酶 II(Pol II)起始前复合物(PIC)的一个组成部分。在这里,我们报道了来自智人的 TFIIS LW 结构域的共振分配,以进一步了解其结构与功能之间的关系。